Carfilzomib-Induced Hypertension Is Mediated By Ion Channel Dysregulation in the Kidneys; The Potent Role of AMP-Activated Kinase α

Introduction: Carfilzomib (Cfz), an irreversible proteasome inhibitor (PI), is an approved agent against relapsed/refractory multiple myeloma (R/R MM). Cfz is associated with high incidence of cardiovascular adverse effects. Hypertension stands as the most frequent cardiovascular complication of Cfz...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.34-35
Hauptverfasser:	Efentakis, Panagiotis, Lamprou, Sofia, Dimas, Polyzois, Dimitriou, Constantinos, Makridakis, Manousos, Tsoumani, Maria, Papanikolaou, Asimina, Kastritis, Efstathios, Vlachou, Antonia, Dimopoulos, Meletios A, Andreadou, Ioanna, Terpos, Evangelos
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!