Towards Identifying the Target of Autoimmunity in Aplastic Anemia

Acquired aplastic anemia (AA) is an autoimmune bone marrow aplasia caused by T cell-mediated destruction of hematopoietic stem and progenitor cells. The antigenic target in AA remains unknown. Recently, we and others identified frequent somatic loss of function of several human leukocyte antigen (HL...

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Veröffentlicht in:Blood 2020-11, Vol.136 (Supplement 1), p.2-2
Hauptverfasser: Frost, Benjamin F, Duke, Jamie, Xie, Hongbo, Ferriola, Deborah, Oved, Joseph H, Nicholas, Peter, Fan, Jian-Meng, Hausler, Ryan, Bertuch, Alison A., Furutani, Elissa M., Shimamura, Akiko, Lee, Stephanie J., Spellman, Stephen R., Monos, Dimitri S., Olson, Timothy S., Babushok, Daria V.
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Sprache:eng
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