Efficacy and Safety of Voxelotor in Sickle Cell Disease: A Systematic Review

Introduction: Sickle cell disease (SCD) is caused by mutation of beta-globin chain alleles, with the involvement of at least one sickle mutation. Sickling of red cells leads to hemolytic anemia, vaso-occlusions, and inflammation. Voxelotor (GBT440) is a hemoglobin modulator that prevents polymerizat...

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Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.35-35
Hauptverfasser:	Ali, Muhammad Ashar, Khan, Anam, Khan, Sana Irfan, Aamir, Sobia, Rahman, Saad Ur, Waqar, Anum, Chaudry, Hafsa Tahir, Anwar, Muhammad Yasir, Aiman, Wajeeha, Anwer, Faiz
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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