Resolution of Serious Vaso-Occlusive Pain Crises and Reduction in Patient-Reported Pain Intensity: Results from the Ongoing Phase 1/2 HGB-206 Group C Study of LentiGlobin for Sickle Cell Disease (bb1111) Gene Therapy

Background Sickle cell disease (SCD) is caused by abnormal sickle hemoglobin (HbS) and results in chronic hemolytic anemia, painful vaso-occlusive events (VOEs), and progressive vasculopathy that lead to significant morbidity. While acute vaso-occlusive pain is a defining clinical feature, chronic d...

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Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.16-17
Hauptverfasser:	Thompson, Alexis A., Walters, Mark C., Mapara, Markus Y, Kwiatkowski, Janet L., Krishnamurti, Lakshmanan, Aygun, Banu, Kasow, Kimberly A., Rifkin-Zenenberg, Stacey, Schmidt, Manfred, DelCarpini, Jay, Pierciey, Francis J., Miller, Alexandra L., Gallagher, Meghan E., Chen, Ren, Goyal, Sunita, Kanter, Julie, Tisdale, John F.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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