An Integrative Genomic Approach to Examine Mutations and Biological Pathways Associated with Hematological Malignancy Development in DDX41 Mutated Families

DEAD-Box helicase 41 (DDX41) is one of the most commonly reported familial hematological malignancy (HM) genes, first reported in 2015. Mutated, it predisposes to both MDS/AML and lymphoma with an age of diagnosis similar to that of sporadic cases. Consequently, unrecognized DDX41 mutated cases are...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.2686-2686
Hauptverfasser:	Venugopal, Parvathy, Cheah, Jesse JC, Eshraghi, Leila, Shahrin, Nur Hezrin, Homan, Claire, Feng, Jinghua, Schreiber, Andreas W, Fine, Miriam, Phillips, Kerry, Poplawski, Nicola, Brown, Anna L, Hahn, Christopher N, Scott, Hamish S
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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