Analysis of Metformin Effects on Bone Marrow Fibrosis and Disease Progression in Primary Myelofibrosis Patients: Preliminary Results of an Open Label Phase II Trial (FIBROMET)

Background: Primary Myelofibrosis (PMF) is a chronic myeloproliferative neoplasm (MPN) characterized by increased myeloid proliferation and associated with mutations that induce tyrosine-kinase activation mainly via JAK-STAT pathway, culminating in extensive bone marrow (BM) fibrosis in the course o...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.554-554
Hauptverfasser:	Campos, Paula De Melo, Pagnano, Katia B, Mancuso, Rubia, Teófilo, Francisco Breno S., Coelho-Silva, Juan L, Della Via, Fernanda I, Freitas, Leandro Luiz Lopes, Carvalho, Hernandes F., Costa, Fernando Ferreira, Traina, Fabiola, Olalla Saad, Sara T
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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