Immune Profiling of Relapsed/Refractory Multiple Myeloma Patients Treated with Venetoclax in Combination with Dexamethasone (VenDex), Daratumumab and Dexamethasone (VenDd), and Daratumumab, Bortezomib and Dexamethasone (VenDVd)

▪ Background: The BCL-2 family of anti-apoptotic proteins (e.g., BCL-2, BCL-XL, MCL-1) are important regulators of lymphocyte development and are therapeutic targets for hematologic malignancies, including multiple myeloma (MM). Venetoclax (Ven) is a highly selective, potent, oral BCL-2 inhibitor th...

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Veröffentlicht in:Blood 2019-11, Vol.134 (Supplement_1), p.1896-1896
Hauptverfasser: Vishwamitra, Deeksha, Mantis, Christine, Haribhai, Dipica, Uziel, Tamar, Leverson, Joel D., Pauff, James M., Bueno, Orlando F., Maciag, Paulo C., Ross, Jeremy A.
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Sprache:eng
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