Vls-101 Is a Novel Therapeutic Antibody-Drug Conjugate (ADC) Targeting Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) in Richter's Syndrome (RS)

ROR1 is a transmembrane receptor with tightly controlled expression during development. It is present on multiple tumor types but not on normal adult tissues. Hematological malignancies are often ROR1-positive, including chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), and diffuse lar...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.2856-2856
Hauptverfasser:	Vaisitti, Tiziana, Jessen, Katti, Vo, Thanh-Trang, Ko, Mira, Arruga, Francesca, Vitale, Nicoletta, Braggio, Esteban, Di Napoli, Arianna, Chadburn, Amy, Allan, John N., Furman, Richard R., Miller, Langdon L., Lanutti, Brian J, Deaglio, Silvia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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