Fetal Hemoglobin Measurement per Red Blood Cell Provides Biological and Clinical Protective Thresholds

Introduction: Fetal hemoglobin (HbF) expression is a major modulator of sickle cell disease (SCD) severity by decreasing the HbS polymerization. However, the distribution of HbF in red blood cells (RBC) is heterogeneous in SCD patients. In the hypothesis of an HbF “threshold” in RBCs for inhibiting...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.1008-1008
Hauptverfasser:	Hebert, Nicolas, Marie Georgine, Rakotoson, Bodivit, Gwellaouen, Audureau, Etienne, Oubaya, Nadia, Pakdaman, Sadaf, Sakka, Mehdi, Di Liberto, Gaetana, Chadebech, Philippe, Vingert, Benoît, Pirenne, France, Galactéros, Frédéric, Cambot, Marie, Bartolucci, Pablo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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