Up-Regulation of the mRNA Expression and Plasma Activity of PADI4in Sickle Cell Anemia during Acute Crisis

Introduction: Recent evidence suggests that coagulation activation is involved in the pathogenesis of progressive organ failure in Sickle Cell Anemia (SCA). In addition, generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, has been associated with the pa...

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Veröffentlicht in:Blood 2019-11, Vol.134 (Supplement_1), p.2257-2257
Hauptverfasser: Hounkpe, Bidossessi Wilfried, Chenou, Francine, Domingos, Igor de Farias, Cardoso, Evilazio Cunha, Sobreira, Marcondes José de Vasconcelos Costa, Araujo, Aderson da Silva, Lucena-Araújo, Antonio Roberto, Neto, Pedro Vieira da Silva, Malheiro, Adriana, Fraiji, Nelson Abrahim, Costa, Fernando Ferreira, Bezerra, Marcos André Cavalcanti, Santos, Magnun Nueldo Nunes, De Paula, Erich V
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Sprache:eng
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