Targeted FGFR Inhibition Results in Hematologic and Cytogenetic Remission in a Myeloid Neoplasm Driven By a Novel PCM1-FGFR1 Fusion: Data from an Expanded Access Program

Introduction In 2008, the World Health Organization defined a new classification of myeloid and lymphoid neoplasms with eosinophilia that result from gene rearrangements of PDGFRA, PDGFRB, and FGFR1. While rearrangements involving PDGFRA and PDGFRB generally respond well to imatinib, those associate...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.5371-5371
Hauptverfasser:	Kasbekar, Monica, Nardi, Valentina, Dal Cin, Paola, Brunner, Andrew M., Chen, Yi-Bin, Connolly, Christine, Fathi, Amir T., Foster, Julia, Macrae, Molly, McAfee, Steven L, McGregor, Kristin, Narayan, Rupa, Ramos, Aura Y., Som, Tina T., Vartanian, Megan, Friedman, Robb S, Benhadji, Karim, Hobbs, Gabriela S.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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