Prognostic Impact of Chromosomal Abnormalities and Copy Number Alterations Among Adults with B-Cell Precursor Acute Lymphoblastic Leukaemia Treated on UKALL14

Chromosomal abnormalities are established prognostic markers in adult ALL. Analysis of the UKALLXII/ECOG2993 trial (Blood, 2007;109:3189) revealed that patients (15-65 years) with BCR-ABL1, KMT2A-AFF1, low hypodiploidy (HoL) or a complex karyotype (CK) had a significantly inferior outcome in multiva...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.288-288
Hauptverfasser:	Moorman, Anthony V., Butler, Ellie, Barretta, Emilio, Kirkwood, Amy A., Schwab, Claire, Creasey, Thomas, Leongamornlert, Daniel A., Papaemmanuil, Elli, Patrick, Pip, Clifton-Hadley, Laura, Wrench, Bela, Menne, Tobias F, McMillan, Andrew K, Harrison, Christine J., Rowntree, Clare J, Marks, David I, Fielding, Adele K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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