A Phase I/II Dose-Escalation Study of Thiotepa-Based Immunochemotherapy in Relapsed/Refractory Primary Central Nervous System Lymphoma; The Tier Trial

BACKGROUND Outcomes for patients (pts) with primary CNS diffuse large B cell lymphoma (PCNSL) have improved over recent years, largely through optimisation of first-line methotrexate (MTX)-containing protocols and dose-intensive chemotherapy consolidation. However, 30-50% of pts experience refractor...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (Supplement_1), p.2879-2879
Hauptverfasser:	Fox, Christopher P, Ali, Ayesha S, Auer, Dorothee, Thust, Steffi, Jackson, Aimee E, Hopkins, Louise, Thomas, Catherine, Martinez-Calle, Nicolas, Collins, Graham P., Kassam, Shireen, Wright, Josh, Lewis, David, Ferreri, Andres JM, Chaganti, Sridhar, Smith, Jeffery, Linton, Kim, Chau, Ian, Culligan, Dominic J., Davies, Andrew, Johnson, Roderick, Cwynarski, Kate
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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