Thrombosis in myeloproliferative and myelodysplastic syndromes
Myeloproliferative neoplasms (MPNs) and myelodisplastic syndromes (MDs) are clonal disorders caused by mutations of myeloid stem cells. Among MPNs, polycythemia vera and essential thrombocythemia are relatively benign disorders in which arterial and venous thromboses represent the main cause of morb...
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| Veröffentlicht in: | Hematology (Luxembourg) 2012-04, Vol.17 (sup1), p.s174-s176 |
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| creator | Landolfi, Raffaele Gennaro, Leonardo Di |
| description | Myeloproliferative neoplasms (MPNs) and myelodisplastic syndromes (MDs) are clonal disorders caused by mutations of myeloid stem cells. Among MPNs, polycythemia vera and essential thrombocythemia are relatively benign disorders in which arterial and venous thromboses represent the main cause of morbidity and mortality. The natural history of MDs is often complicated by both thromboses and haemorrhages, mainly due to platelet quantitative and quantitative anomalies, as well as to treatment complications. In this short review, we focus the attention on the main aspects of thrombophilia in both disorders. |
| doi_str_mv | 10.1179/102453312X13336169156898 |
| format | Article |
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In this short review, we focus the attention on the main aspects of thrombophilia in both disorders.</description><subject>Clonal disorders</subject><subject>Humans</subject><subject>Myelodisplastic syndromes</subject><subject>Myelodysplastic Syndromes - complications</subject><subject>Myeloproliferative Disorders - complications</subject><subject>Myeloproliferative neoplasms</subject><subject>Risk Factors</subject><subject>Thrombophilia - etiology</subject><subject>Thrombophilia - pathology</subject><subject>Thrombophilia - therapy</subject><subject>Thrombosis</subject><subject>Thrombosis - etiology</subject><subject>Thrombosis - pathology</subject><subject>Thrombosis - therapy</subject><issn>1607-8454</issn><issn>1607-8454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE9LxDAQxYMo7rr6FaRHL9X8bZKLIIurwoKXFbyVJE0xkjZr0lX67Y10FS_iaYaZ35s3PAAKBC8R4vIKQUwZIQg_I0JIhSqJWCWkOABzVEFeCsro4a9-Bk5SeoUQY8jhMZhhzCAXiMzB9eYlhk6H5FLh-qIbrQ_bGLxrbVSDe7eF6ptp3Ixp61UanCnS2DdZZtMpOGqVT_ZsXxfgaXW7Wd6X68e7h-XNujRUoqEkRpiWMo1pxbhBlAkjcWW15ExBzbG1VCvOoMaaalahhpO8EC3DSkJEDFmAi-lu_u1tZ9NQdy4Z673qbdilGkEoWc5EyoyKCTUxpBRtW2-j61QcM1R_pVf_lV6Wnu9ddrqzzY_wO64MLCfA9W2InfoI0Tf1oEYfYhtVb1yqyb82n6kJf2c</recordid><startdate>20120401</startdate><enddate>20120401</enddate><creator>Landolfi, Raffaele</creator><creator>Gennaro, Leonardo Di</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120401</creationdate><title>Thrombosis in myeloproliferative and myelodysplastic syndromes</title><author>Landolfi, Raffaele ; Gennaro, Leonardo Di</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-3c8cf45b24657c1458c926eb975a0b72ee4ba750b2b4b561d735a08f52a9013c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Clonal disorders</topic><topic>Humans</topic><topic>Myelodisplastic syndromes</topic><topic>Myelodysplastic Syndromes - complications</topic><topic>Myeloproliferative Disorders - complications</topic><topic>Myeloproliferative neoplasms</topic><topic>Risk Factors</topic><topic>Thrombophilia - etiology</topic><topic>Thrombophilia - pathology</topic><topic>Thrombophilia - therapy</topic><topic>Thrombosis</topic><topic>Thrombosis - etiology</topic><topic>Thrombosis - pathology</topic><topic>Thrombosis - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Landolfi, Raffaele</creatorcontrib><creatorcontrib>Gennaro, Leonardo Di</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Hematology (Luxembourg)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Landolfi, Raffaele</au><au>Gennaro, Leonardo Di</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thrombosis in myeloproliferative and myelodysplastic syndromes</atitle><jtitle>Hematology (Luxembourg)</jtitle><addtitle>Hematology</addtitle><date>2012-04-01</date><risdate>2012</risdate><volume>17</volume><issue>sup1</issue><spage>s174</spage><epage>s176</epage><pages>s174-s176</pages><issn>1607-8454</issn><eissn>1607-8454</eissn><abstract>Myeloproliferative neoplasms (MPNs) and myelodisplastic syndromes (MDs) are clonal disorders caused by mutations of myeloid stem cells. 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| issn | 1607-8454 1607-8454 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Clonal disorders Humans Myelodisplastic syndromes Myelodysplastic Syndromes - complications Myeloproliferative Disorders - complications Myeloproliferative neoplasms Risk Factors Thrombophilia - etiology Thrombophilia - pathology Thrombophilia - therapy Thrombosis Thrombosis - etiology Thrombosis - pathology Thrombosis - therapy |
| title | Thrombosis in myeloproliferative and myelodysplastic syndromes |
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