Hydrogen sulfide alleviates cigarette smoke-induced COPD through inhibition of the TGF- β 1/smad pathway

Smoking has become a major cause of chronic obstructive pulmonary disease through weakening of the respiratory mucus-ciliary transport system, impairing cough reflex sensitivity, and inducing inflammation. Recent researches have indicated that hydrogen sulfide is essential in the development of vari...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2020-02, Vol.245 (3), p.190-200
Hauptverfasser:	Wang, Liang, Meng, Jing, Wang, Caicai, Yang, Chao, Wang, Yuan, Li, Yamei, Li, Yujing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Hydrogen Sulfide - pharmacology Male Pulmonary Disease, Chronic Obstructive - chemically induced Pulmonary Disease, Chronic Obstructive - drug therapy Rats, Sprague-Dawley Signal Transduction Smad3 Protein - metabolism Smoke - adverse effects Smoking - adverse effects Smoking - metabolism Transforming Growth Factor beta1 - drug effects Transforming Growth Factor beta1 - metabolism
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