Antioxidants and Phase 2 Enzymes in Cardiomyocytes: Chemical Inducibility and Chemoprotection Against Oxidant and Simulated Ischemia-Reperfusion Injury

The increasing recognition of the role for oxidative stress in cardiac disorders has led to extensive investigation on the protection by exogenous antioxidants against oxidative cardiac injury. On the other hand, another strategy for protecting against oxidative cardiac injury may be through upregul...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2006-09, Vol.231 (8), p.1353-1364
Hauptverfasser:	Cao, Zhuoxiao, Zhu, Hong, Zhang, Li, Zhao, Xue, Zweier, Jay L., Li, Yunbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Blotting, Western Catalase - drug effects Catalase - metabolism Cell Line Glutathione - drug effects Glutathione - metabolism Glutathione Peroxidase - drug effects Glutathione Peroxidase - metabolism Glutathione Reductase - drug effects Glutathione Reductase - metabolism Glutathione Transferase - drug effects Glutathione Transferase - metabolism Myocytes, Cardiac - drug effects NAD(P)H Dehydrogenase (Quinone) - drug effects NAD(P)H Dehydrogenase (Quinone) - metabolism Oxidants - adverse effects Oxidative Stress - drug effects Rats Reperfusion Injury - prevention & control Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Superoxide Dismutase - drug effects Superoxide Dismutase - metabolism Thiones - adverse effects
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