Early Results of Elective Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms With the Minos TM Stent-Graft System
A variety of last-generation endografts are currently available for standard endovascular repair (EVAR) of infrarenal abdominal aortic aneurysms (AAAs). The purpose of this study is to report the preliminary clinical outcomes of the Minos trimodular stent-graft system, which was recently introduced...
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| Veröffentlicht in: | Journal of endovascular therapy 2025-02, Vol.32 (1), p.225-232 |
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| creator | Pitoulias, Georgios A Pitoulias, Apostolos G Chatzelas, Dimitrios A Zampaka, Theodosia Loutradis, Charalampos Potouridis, Anastasios Tachtsi, Maria D |
| description | A variety of last-generation endografts are currently available for standard endovascular repair (EVAR) of infrarenal abdominal aortic aneurysms (AAAs). The purpose of this study is to report the preliminary clinical outcomes of the Minos trimodular stent-graft system, which was recently introduced to the European market.
Between February 2020 and 2022, we treated 41 consecutive AAA patients (mean age 72.2±8.5, 37 males) with elective standard EVAR using the Minos. The mean maximum diameter of AAAs was 54.7±6.6 mm, the mean proximal neck's (PN) diameter was 24.8±2.7 mm, while the relevant length and angulation were 16.0 mm and 21.7°, respectively. Overall, 22 (53.6%) patients presented with shorter and angulated PN, according to the stent-graft's instructions of use, and in 6 (14.6%) patients the PN angulation >60° was combined with concomitant iliac angulation >60°. Eleven (26.8%) EVARs were performed with concomitant enormous iliac artery narrowing and tortuosity. Finally, in 19 (46.3%) AAAs, the distal iliac landing zone was aneurysmatic and they were treated with the bell-bottom technique in 17 patients and with limb extension to the external iliac artery in two cases. We evaluated technical and clinical success of the index procedures, which was based on the combination of five factors: freedom from EVAR-related mortality, from graft-related endoleak of any type, from migration at any part of graft as well the absence of notable increase AAA's sac maximum diameter and the patency of bifurcated stent-graft and of access vessels.
Primary technical and clinical success of index procedures was 100%. During a median 12-month radiological follow-up the clinical success remained 100%. No type I or III endoleak, stent-graft migration, EVAR-related death, AAA rupture, or graft-related adverse events or reinterventions were documented. Four (9.8%) type II endoleaks were detected with stable AAA sac diameter. The overall incidence of sac regression was 34.1% (n=14).
The preliminary results of our series showed that Minos provided excellent feasibility and safety features even through angulated and tortuous iliac vessels and in short and angulated PNs. The overall clinical success at 1 year suggests that performance of Minos follows very high standards. Further validation of these promising results with long-term data is acquired to complete the evaluation of this recently introduced stent-graft system.
The current study explored the clinical performance of a new |
| doi_str_mv | 10.1177/15266028231172379 |
| format | Article |
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Between February 2020 and 2022, we treated 41 consecutive AAA patients (mean age 72.2±8.5, 37 males) with elective standard EVAR using the Minos. The mean maximum diameter of AAAs was 54.7±6.6 mm, the mean proximal neck's (PN) diameter was 24.8±2.7 mm, while the relevant length and angulation were 16.0 mm and 21.7°, respectively. Overall, 22 (53.6%) patients presented with shorter and angulated PN, according to the stent-graft's instructions of use, and in 6 (14.6%) patients the PN angulation >60° was combined with concomitant iliac angulation >60°. Eleven (26.8%) EVARs were performed with concomitant enormous iliac artery narrowing and tortuosity. Finally, in 19 (46.3%) AAAs, the distal iliac landing zone was aneurysmatic and they were treated with the bell-bottom technique in 17 patients and with limb extension to the external iliac artery in two cases. We evaluated technical and clinical success of the index procedures, which was based on the combination of five factors: freedom from EVAR-related mortality, from graft-related endoleak of any type, from migration at any part of graft as well the absence of notable increase AAA's sac maximum diameter and the patency of bifurcated stent-graft and of access vessels.
Primary technical and clinical success of index procedures was 100%. During a median 12-month radiological follow-up the clinical success remained 100%. No type I or III endoleak, stent-graft migration, EVAR-related death, AAA rupture, or graft-related adverse events or reinterventions were documented. Four (9.8%) type II endoleaks were detected with stable AAA sac diameter. The overall incidence of sac regression was 34.1% (n=14).
The preliminary results of our series showed that Minos provided excellent feasibility and safety features even through angulated and tortuous iliac vessels and in short and angulated PNs. The overall clinical success at 1 year suggests that performance of Minos follows very high standards. Further validation of these promising results with long-term data is acquired to complete the evaluation of this recently introduced stent-graft system.
The current study explored the clinical performance of a new in market ultra-low profile bifurcated abdominal aortic stent-graft, the MINOS. The early and 12-month results of study suggest that implantation of this stent-graft in standard EVAR, even in hostile proximal aortic neck and iliac vessels conditions, follows very high clinical standards and encourage the further clinical use of MINOS.</description><identifier>ISSN: 1526-6028</identifier><identifier>EISSN: 1545-1550</identifier><identifier>DOI: 10.1177/15266028231172379</identifier><identifier>PMID: 37166154</identifier><language>eng</language><publisher>United States</publisher><subject>Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal - diagnostic imaging ; Aortic Aneurysm, Abdominal - mortality ; Aortic Aneurysm, Abdominal - surgery ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - instrumentation ; Elective Surgical Procedures ; Endoleak - etiology ; Endovascular Procedures - adverse effects ; Endovascular Procedures - instrumentation ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications - etiology ; Prosthesis Design ; Retrospective Studies ; Risk Factors ; Stents ; Time Factors ; Treatment Outcome</subject><ispartof>Journal of endovascular therapy, 2025-02, Vol.32 (1), p.225-232</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1134-b468bbd95024b108dbc40e0fa22c76c16f1a879c85c439b324d47b8cc4d64eb13</citedby><cites>FETCH-LOGICAL-c1134-b468bbd95024b108dbc40e0fa22c76c16f1a879c85c439b324d47b8cc4d64eb13</cites><orcidid>0000-0002-1957-5539 ; 0000-0002-6862-2709 ; 0000-0003-4999-7561</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37166154$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pitoulias, Georgios A</creatorcontrib><creatorcontrib>Pitoulias, Apostolos G</creatorcontrib><creatorcontrib>Chatzelas, Dimitrios A</creatorcontrib><creatorcontrib>Zampaka, Theodosia</creatorcontrib><creatorcontrib>Loutradis, Charalampos</creatorcontrib><creatorcontrib>Potouridis, Anastasios</creatorcontrib><creatorcontrib>Tachtsi, Maria D</creatorcontrib><title>Early Results of Elective Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms With the Minos TM Stent-Graft System</title><title>Journal of endovascular therapy</title><addtitle>J Endovasc Ther</addtitle><description>A variety of last-generation endografts are currently available for standard endovascular repair (EVAR) of infrarenal abdominal aortic aneurysms (AAAs). The purpose of this study is to report the preliminary clinical outcomes of the Minos trimodular stent-graft system, which was recently introduced to the European market.
Between February 2020 and 2022, we treated 41 consecutive AAA patients (mean age 72.2±8.5, 37 males) with elective standard EVAR using the Minos. The mean maximum diameter of AAAs was 54.7±6.6 mm, the mean proximal neck's (PN) diameter was 24.8±2.7 mm, while the relevant length and angulation were 16.0 mm and 21.7°, respectively. Overall, 22 (53.6%) patients presented with shorter and angulated PN, according to the stent-graft's instructions of use, and in 6 (14.6%) patients the PN angulation >60° was combined with concomitant iliac angulation >60°. Eleven (26.8%) EVARs were performed with concomitant enormous iliac artery narrowing and tortuosity. Finally, in 19 (46.3%) AAAs, the distal iliac landing zone was aneurysmatic and they were treated with the bell-bottom technique in 17 patients and with limb extension to the external iliac artery in two cases. We evaluated technical and clinical success of the index procedures, which was based on the combination of five factors: freedom from EVAR-related mortality, from graft-related endoleak of any type, from migration at any part of graft as well the absence of notable increase AAA's sac maximum diameter and the patency of bifurcated stent-graft and of access vessels.
Primary technical and clinical success of index procedures was 100%. During a median 12-month radiological follow-up the clinical success remained 100%. No type I or III endoleak, stent-graft migration, EVAR-related death, AAA rupture, or graft-related adverse events or reinterventions were documented. Four (9.8%) type II endoleaks were detected with stable AAA sac diameter. The overall incidence of sac regression was 34.1% (n=14).
The preliminary results of our series showed that Minos provided excellent feasibility and safety features even through angulated and tortuous iliac vessels and in short and angulated PNs. The overall clinical success at 1 year suggests that performance of Minos follows very high standards. Further validation of these promising results with long-term data is acquired to complete the evaluation of this recently introduced stent-graft system.
The current study explored the clinical performance of a new in market ultra-low profile bifurcated abdominal aortic stent-graft, the MINOS. The early and 12-month results of study suggest that implantation of this stent-graft in standard EVAR, even in hostile proximal aortic neck and iliac vessels conditions, follows very high clinical standards and encourage the further clinical use of MINOS.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Aneurysm, Abdominal - diagnostic imaging</subject><subject>Aortic Aneurysm, Abdominal - mortality</subject><subject>Aortic Aneurysm, Abdominal - surgery</subject><subject>Blood Vessel Prosthesis</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Blood Vessel Prosthesis Implantation - instrumentation</subject><subject>Elective Surgical Procedures</subject><subject>Endoleak - etiology</subject><subject>Endovascular Procedures - adverse effects</subject><subject>Endovascular Procedures - instrumentation</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications - etiology</subject><subject>Prosthesis Design</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Stents</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>1526-6028</issn><issn>1545-1550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkF1LwzAUhoMobk5_gDeSP1DNSdK0vRyjzsGG4CZeliRNWaUfI0kHxT-_1qk3Xp33cJ73XDwI3QN5BIiiJwipEITGlA0rZVFygaYQ8jCAMCSXY6YiGIEJunHukxAKFOAaTVgEQgzkFH2l0lY9fjOuq7zDbYHTymhfHg1Om7w9Sqe7StoBOMjSjvdVU1hpTSMrPFd5W5ffqbW-1HjemM72rnb4o_R77PcGb8qmdXi3wVtvGh8srSw83vbOm_oWXRWycubuZ87Q-3O6W7wE69flajFfBxqA8UBxESuVJyGhXAGJc6U5MaSQlOpIaBAFyDhKdBxqzhLFKM95pGKteS64UcBmCM5_tW2ds6bIDraspe0zINkoMvsncug8nDuHTtUm_2v8mmMnwbtunQ</recordid><startdate>202502</startdate><enddate>202502</enddate><creator>Pitoulias, Georgios A</creator><creator>Pitoulias, Apostolos G</creator><creator>Chatzelas, Dimitrios A</creator><creator>Zampaka, Theodosia</creator><creator>Loutradis, Charalampos</creator><creator>Potouridis, Anastasios</creator><creator>Tachtsi, Maria D</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-1957-5539</orcidid><orcidid>https://orcid.org/0000-0002-6862-2709</orcidid><orcidid>https://orcid.org/0000-0003-4999-7561</orcidid></search><sort><creationdate>202502</creationdate><title>Early Results of Elective Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms With the Minos TM Stent-Graft System</title><author>Pitoulias, Georgios A ; Pitoulias, Apostolos G ; Chatzelas, Dimitrios A ; Zampaka, Theodosia ; Loutradis, Charalampos ; Potouridis, Anastasios ; Tachtsi, Maria D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1134-b468bbd95024b108dbc40e0fa22c76c16f1a879c85c439b324d47b8cc4d64eb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Aneurysm, Abdominal - diagnostic imaging</topic><topic>Aortic Aneurysm, Abdominal - mortality</topic><topic>Aortic Aneurysm, Abdominal - surgery</topic><topic>Blood Vessel Prosthesis</topic><topic>Blood Vessel Prosthesis Implantation - adverse effects</topic><topic>Blood Vessel Prosthesis Implantation - instrumentation</topic><topic>Elective Surgical Procedures</topic><topic>Endoleak - etiology</topic><topic>Endovascular Procedures - adverse effects</topic><topic>Endovascular Procedures - instrumentation</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications - etiology</topic><topic>Prosthesis Design</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Stents</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pitoulias, Georgios A</creatorcontrib><creatorcontrib>Pitoulias, Apostolos G</creatorcontrib><creatorcontrib>Chatzelas, Dimitrios A</creatorcontrib><creatorcontrib>Zampaka, Theodosia</creatorcontrib><creatorcontrib>Loutradis, Charalampos</creatorcontrib><creatorcontrib>Potouridis, Anastasios</creatorcontrib><creatorcontrib>Tachtsi, Maria D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of endovascular therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pitoulias, Georgios A</au><au>Pitoulias, Apostolos G</au><au>Chatzelas, Dimitrios A</au><au>Zampaka, Theodosia</au><au>Loutradis, Charalampos</au><au>Potouridis, Anastasios</au><au>Tachtsi, Maria D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early Results of Elective Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms With the Minos TM Stent-Graft System</atitle><jtitle>Journal of endovascular therapy</jtitle><addtitle>J Endovasc Ther</addtitle><date>2025-02</date><risdate>2025</risdate><volume>32</volume><issue>1</issue><spage>225</spage><epage>232</epage><pages>225-232</pages><issn>1526-6028</issn><eissn>1545-1550</eissn><abstract>A variety of last-generation endografts are currently available for standard endovascular repair (EVAR) of infrarenal abdominal aortic aneurysms (AAAs). The purpose of this study is to report the preliminary clinical outcomes of the Minos trimodular stent-graft system, which was recently introduced to the European market.
Between February 2020 and 2022, we treated 41 consecutive AAA patients (mean age 72.2±8.5, 37 males) with elective standard EVAR using the Minos. The mean maximum diameter of AAAs was 54.7±6.6 mm, the mean proximal neck's (PN) diameter was 24.8±2.7 mm, while the relevant length and angulation were 16.0 mm and 21.7°, respectively. Overall, 22 (53.6%) patients presented with shorter and angulated PN, according to the stent-graft's instructions of use, and in 6 (14.6%) patients the PN angulation >60° was combined with concomitant iliac angulation >60°. Eleven (26.8%) EVARs were performed with concomitant enormous iliac artery narrowing and tortuosity. Finally, in 19 (46.3%) AAAs, the distal iliac landing zone was aneurysmatic and they were treated with the bell-bottom technique in 17 patients and with limb extension to the external iliac artery in two cases. We evaluated technical and clinical success of the index procedures, which was based on the combination of five factors: freedom from EVAR-related mortality, from graft-related endoleak of any type, from migration at any part of graft as well the absence of notable increase AAA's sac maximum diameter and the patency of bifurcated stent-graft and of access vessels.
Primary technical and clinical success of index procedures was 100%. During a median 12-month radiological follow-up the clinical success remained 100%. No type I or III endoleak, stent-graft migration, EVAR-related death, AAA rupture, or graft-related adverse events or reinterventions were documented. Four (9.8%) type II endoleaks were detected with stable AAA sac diameter. The overall incidence of sac regression was 34.1% (n=14).
The preliminary results of our series showed that Minos provided excellent feasibility and safety features even through angulated and tortuous iliac vessels and in short and angulated PNs. The overall clinical success at 1 year suggests that performance of Minos follows very high standards. Further validation of these promising results with long-term data is acquired to complete the evaluation of this recently introduced stent-graft system.
The current study explored the clinical performance of a new in market ultra-low profile bifurcated abdominal aortic stent-graft, the MINOS. The early and 12-month results of study suggest that implantation of this stent-graft in standard EVAR, even in hostile proximal aortic neck and iliac vessels conditions, follows very high clinical standards and encourage the further clinical use of MINOS.</abstract><cop>United States</cop><pmid>37166154</pmid><doi>10.1177/15266028231172379</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-1957-5539</orcidid><orcidid>https://orcid.org/0000-0002-6862-2709</orcidid><orcidid>https://orcid.org/0000-0003-4999-7561</orcidid></addata></record> |
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| ispartof | Journal of endovascular therapy, 2025-02, Vol.32 (1), p.225-232 |
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| language | eng |
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| source | SAGE Complete A-Z List; MEDLINE |
| subjects | Aged Aged, 80 and over Aortic Aneurysm, Abdominal - diagnostic imaging Aortic Aneurysm, Abdominal - mortality Aortic Aneurysm, Abdominal - surgery Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation - adverse effects Blood Vessel Prosthesis Implantation - instrumentation Elective Surgical Procedures Endoleak - etiology Endovascular Procedures - adverse effects Endovascular Procedures - instrumentation Female Humans Male Middle Aged Postoperative Complications - etiology Prosthesis Design Retrospective Studies Risk Factors Stents Time Factors Treatment Outcome |
| title | Early Results of Elective Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms With the Minos TM Stent-Graft System |
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