ISDR pattern and evolution in patients with chronic hepatitis C treated with standard or Peg-IFN plus ribavirin

The aim of the study was to characterize the interferon sensitivity determining region (ISDR) mutation pattern and its changes at 4 weeks of treatment in a population of patients infected with hepatitis C virus (HCV) genotype 1b receiving standard or PEG-IFN plus ribavirin (RBV), to find possible ea...

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Veröffentlicht in:	Antiviral therapy 2003-04, Vol.8 (2), p.105-110
Hauptverfasser:	CAPPIELLO, Giuseppina, ABBATE, Isabella, IPPOLITO, Giuseppe, CAPOBIANCHI, Maria Rosaria, LO LACONO, Oreste, LONGO, Roberta, SOLMONE, Mariacarmela, FERRARO, Donatella, ANTONUCCI, Giorgio, DI MARCO, Vito, DI STEFANO, Rosa, CRAXI, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Antiviral Agents - therapeutic use Biological and medical sciences Cohort Studies Drug Therapy, Combination Female Genotype Hepacivirus - drug effects Hepacivirus - genetics Hepatitis C, Chronic - drug therapy Humans Interferon alpha-2 Interferon-alpha - therapeutic use Male Medical sciences Middle Aged Molecular Sequence Data Mutation Pharmacology. Drug treatments Polyethylene Glycols - therapeutic use Recombinant Proteins Ribavirin - therapeutic use Sequence Alignment Treatment Outcome Viral Nonstructural Proteins - genetics
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