Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis

The object of this study was to monitor the safety and efficacy of long-term use of an oromucosal cannabis-based medicine (CBM) in patients with multiple sclerosis (MS). A total of 137 MS patients with symptoms not controlled satisfactorily using standard drugs entered this open-label trial followin...

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Veröffentlicht in:	Multiple sclerosis 2006-10, Vol.12 (5), p.639-645
Hauptverfasser:	Wade, D T, Makela, P M, House, H, Bateman, C, Robson, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analgesics - administration & dosage Analgesics - adverse effects Biological and medical sciences Cannabinoids - administration & dosage Cannabinoids - adverse effects Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Double-Blind Method Drug Administration Schedule Female Humans Immunomodulators Male Medical sciences Middle Aged Multiple Sclerosis - complications Multiple Sclerosis - drug therapy Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Muscle Spasticity - drug therapy Muscle Spasticity - etiology Neurology Pain Measurement Pharmacology. Drug treatments Phytotherapy Plant Preparations - administration & dosage Plant Preparations - adverse effects Time Factors Treatment Outcome
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