The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis
Purpose: To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review the therapeutic role of pars plana vitrectomy in patients with fungal endogenous endophthalmitis. Methods: Seven eyes of six cases were identified as fungal endoge...
Gespeichert in:
| Veröffentlicht in: | European journal of ophthalmology 2020-01, Vol.30 (1), p.88-93 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 93 |
|---|---|
| container_issue | 1 |
| container_start_page | 88 |
| container_title | European journal of ophthalmology |
| container_volume | 30 |
| creator | Celiker, Hande Kazokoglu, Haluk |
| description | Purpose:
To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review the therapeutic role of pars plana vitrectomy in patients with fungal endogenous endophthalmitis.
Methods:
Seven eyes of six cases were identified as fungal endogenous endophthalmitis through positive cultures of ocular fluids and clinical presentations. The final anatomical and functional results were evaluated.
Results:
Four women (66.7%) and two men (33.3%) underwent vitrectomy. Control of infection was achieved early on in all cases. Candida (71.4%) and Aspergillus (28.6%) species were identified as causative fungi in patients with fungal endogenous endophthalmitis. Two patients were reoperated due to reinfection and retinal detachment, respectively. Visual acuity improved in six eyes (85.7%) and worsened in one eye (14.3%). At the final examination, the retina was flat in all cases. No eye developed phthisis bulbi.
Conclusion:
Candida species are the most common causative organisms of fungal endogenous endophthalmitis in this study. Pars plana vitrectomy in fungal endogenous endophthalmitis may enhance the treatment of infection by removing fungal elements in the vitreous and aid in diagnosis. Vitrectomy may also be an important tool in the management of vision-threatening post-infectious sequelae such as retinal detachment and reinfections. |
| doi_str_mv | 10.1177/1120672118815105 |
| format | Article |
| fullrecord | <record><control><sourceid>sage_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1177_1120672118815105</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1120672118815105</sage_id><sourcerecordid>10.1177_1120672118815105</sourcerecordid><originalsourceid>FETCH-LOGICAL-c403t-7fd13759da3a28325d39b84174814c3065c01190a189490f63e203a5e68536413</originalsourceid><addsrcrecordid>eNp1UMtKAzEUDaLYWt27kvzA6L1JJpkspfiCgpsK7oZ0JtNOmRdJRujfmzrqQnB1D_c84BxCrhFuEZW6Q2QgFUPMMkwR0hMyR8VEIgHlacSRTo78jFx4vwdgoAU7JzMOQgmu1Zy8r3eWur6xtK_oYJynQ2M6Qz_q4GwR-vZA646GKGrje2tb24WjtBq7rWmo7cp-a7t-9F9w2IWdado61P6SnFWm8fbq-y7I2-PDevmcrF6fXpb3q6QQwEOiqhK5SnVpuGEZZ2nJ9SYTqESGouAg0wIQNRjMtNBQSW4ZcJNamaVcCuQLAlNu4Xrvna3ywdWtcYccIT-OlP8dKVpuJsswblpb_hp-VomCZBL42Djf96PrYoX_Az8Bx2htdw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis</title><source>MEDLINE</source><source>SAGE Complete A-Z List</source><creator>Celiker, Hande ; Kazokoglu, Haluk</creator><creatorcontrib>Celiker, Hande ; Kazokoglu, Haluk</creatorcontrib><description>Purpose:
To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review the therapeutic role of pars plana vitrectomy in patients with fungal endogenous endophthalmitis.
Methods:
Seven eyes of six cases were identified as fungal endogenous endophthalmitis through positive cultures of ocular fluids and clinical presentations. The final anatomical and functional results were evaluated.
Results:
Four women (66.7%) and two men (33.3%) underwent vitrectomy. Control of infection was achieved early on in all cases. Candida (71.4%) and Aspergillus (28.6%) species were identified as causative fungi in patients with fungal endogenous endophthalmitis. Two patients were reoperated due to reinfection and retinal detachment, respectively. Visual acuity improved in six eyes (85.7%) and worsened in one eye (14.3%). At the final examination, the retina was flat in all cases. No eye developed phthisis bulbi.
Conclusion:
Candida species are the most common causative organisms of fungal endogenous endophthalmitis in this study. Pars plana vitrectomy in fungal endogenous endophthalmitis may enhance the treatment of infection by removing fungal elements in the vitreous and aid in diagnosis. Vitrectomy may also be an important tool in the management of vision-threatening post-infectious sequelae such as retinal detachment and reinfections.</description><identifier>ISSN: 1120-6721</identifier><identifier>EISSN: 1724-6016</identifier><identifier>DOI: 10.1177/1120672118815105</identifier><identifier>PMID: 30474397</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Aged ; Aspergillosis - microbiology ; Aspergillosis - physiopathology ; Aspergillosis - surgery ; Candidiasis - microbiology ; Candidiasis - physiopathology ; Candidiasis - surgery ; Endophthalmitis - microbiology ; Endophthalmitis - physiopathology ; Endophthalmitis - surgery ; Eye Infections, Fungal - microbiology ; Eye Infections, Fungal - physiopathology ; Eye Infections, Fungal - surgery ; Female ; Humans ; Male ; Middle Aged ; Reoperation ; Retinal Detachment - surgery ; Retrospective Studies ; Tertiary Care Centers ; Visual Acuity - physiology ; Vitrectomy - methods ; Vitreous Body - microbiology ; Young Adult</subject><ispartof>European journal of ophthalmology, 2020-01, Vol.30 (1), p.88-93</ispartof><rights>The Author(s) 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-7fd13759da3a28325d39b84174814c3065c01190a189490f63e203a5e68536413</citedby><cites>FETCH-LOGICAL-c403t-7fd13759da3a28325d39b84174814c3065c01190a189490f63e203a5e68536413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1120672118815105$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1120672118815105$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30474397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Celiker, Hande</creatorcontrib><creatorcontrib>Kazokoglu, Haluk</creatorcontrib><title>The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis</title><title>European journal of ophthalmology</title><addtitle>Eur J Ophthalmol</addtitle><description>Purpose:
To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review the therapeutic role of pars plana vitrectomy in patients with fungal endogenous endophthalmitis.
Methods:
Seven eyes of six cases were identified as fungal endogenous endophthalmitis through positive cultures of ocular fluids and clinical presentations. The final anatomical and functional results were evaluated.
Results:
Four women (66.7%) and two men (33.3%) underwent vitrectomy. Control of infection was achieved early on in all cases. Candida (71.4%) and Aspergillus (28.6%) species were identified as causative fungi in patients with fungal endogenous endophthalmitis. Two patients were reoperated due to reinfection and retinal detachment, respectively. Visual acuity improved in six eyes (85.7%) and worsened in one eye (14.3%). At the final examination, the retina was flat in all cases. No eye developed phthisis bulbi.
Conclusion:
Candida species are the most common causative organisms of fungal endogenous endophthalmitis in this study. Pars plana vitrectomy in fungal endogenous endophthalmitis may enhance the treatment of infection by removing fungal elements in the vitreous and aid in diagnosis. Vitrectomy may also be an important tool in the management of vision-threatening post-infectious sequelae such as retinal detachment and reinfections.</description><subject>Adult</subject><subject>Aged</subject><subject>Aspergillosis - microbiology</subject><subject>Aspergillosis - physiopathology</subject><subject>Aspergillosis - surgery</subject><subject>Candidiasis - microbiology</subject><subject>Candidiasis - physiopathology</subject><subject>Candidiasis - surgery</subject><subject>Endophthalmitis - microbiology</subject><subject>Endophthalmitis - physiopathology</subject><subject>Endophthalmitis - surgery</subject><subject>Eye Infections, Fungal - microbiology</subject><subject>Eye Infections, Fungal - physiopathology</subject><subject>Eye Infections, Fungal - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Reoperation</subject><subject>Retinal Detachment - surgery</subject><subject>Retrospective Studies</subject><subject>Tertiary Care Centers</subject><subject>Visual Acuity - physiology</subject><subject>Vitrectomy - methods</subject><subject>Vitreous Body - microbiology</subject><subject>Young Adult</subject><issn>1120-6721</issn><issn>1724-6016</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UMtKAzEUDaLYWt27kvzA6L1JJpkspfiCgpsK7oZ0JtNOmRdJRujfmzrqQnB1D_c84BxCrhFuEZW6Q2QgFUPMMkwR0hMyR8VEIgHlacSRTo78jFx4vwdgoAU7JzMOQgmu1Zy8r3eWur6xtK_oYJynQ2M6Qz_q4GwR-vZA646GKGrje2tb24WjtBq7rWmo7cp-a7t-9F9w2IWdado61P6SnFWm8fbq-y7I2-PDevmcrF6fXpb3q6QQwEOiqhK5SnVpuGEZZ2nJ9SYTqESGouAg0wIQNRjMtNBQSW4ZcJNamaVcCuQLAlNu4Xrvna3ywdWtcYccIT-OlP8dKVpuJsswblpb_hp-VomCZBL42Djf96PrYoX_Az8Bx2htdw</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Celiker, Hande</creator><creator>Kazokoglu, Haluk</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20200101</creationdate><title>The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis</title><author>Celiker, Hande ; Kazokoglu, Haluk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-7fd13759da3a28325d39b84174814c3065c01190a189490f63e203a5e68536413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aspergillosis - microbiology</topic><topic>Aspergillosis - physiopathology</topic><topic>Aspergillosis - surgery</topic><topic>Candidiasis - microbiology</topic><topic>Candidiasis - physiopathology</topic><topic>Candidiasis - surgery</topic><topic>Endophthalmitis - microbiology</topic><topic>Endophthalmitis - physiopathology</topic><topic>Endophthalmitis - surgery</topic><topic>Eye Infections, Fungal - microbiology</topic><topic>Eye Infections, Fungal - physiopathology</topic><topic>Eye Infections, Fungal - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Reoperation</topic><topic>Retinal Detachment - surgery</topic><topic>Retrospective Studies</topic><topic>Tertiary Care Centers</topic><topic>Visual Acuity - physiology</topic><topic>Vitrectomy - methods</topic><topic>Vitreous Body - microbiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Celiker, Hande</creatorcontrib><creatorcontrib>Kazokoglu, Haluk</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>European journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Celiker, Hande</au><au>Kazokoglu, Haluk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis</atitle><jtitle>European journal of ophthalmology</jtitle><addtitle>Eur J Ophthalmol</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>30</volume><issue>1</issue><spage>88</spage><epage>93</epage><pages>88-93</pages><issn>1120-6721</issn><eissn>1724-6016</eissn><abstract>Purpose:
To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review the therapeutic role of pars plana vitrectomy in patients with fungal endogenous endophthalmitis.
Methods:
Seven eyes of six cases were identified as fungal endogenous endophthalmitis through positive cultures of ocular fluids and clinical presentations. The final anatomical and functional results were evaluated.
Results:
Four women (66.7%) and two men (33.3%) underwent vitrectomy. Control of infection was achieved early on in all cases. Candida (71.4%) and Aspergillus (28.6%) species were identified as causative fungi in patients with fungal endogenous endophthalmitis. Two patients were reoperated due to reinfection and retinal detachment, respectively. Visual acuity improved in six eyes (85.7%) and worsened in one eye (14.3%). At the final examination, the retina was flat in all cases. No eye developed phthisis bulbi.
Conclusion:
Candida species are the most common causative organisms of fungal endogenous endophthalmitis in this study. Pars plana vitrectomy in fungal endogenous endophthalmitis may enhance the treatment of infection by removing fungal elements in the vitreous and aid in diagnosis. Vitrectomy may also be an important tool in the management of vision-threatening post-infectious sequelae such as retinal detachment and reinfections.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>30474397</pmid><doi>10.1177/1120672118815105</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1120-6721 |
| ispartof | European journal of ophthalmology, 2020-01, Vol.30 (1), p.88-93 |
| issn | 1120-6721 1724-6016 |
| language | eng |
| recordid | cdi_crossref_primary_10_1177_1120672118815105 |
| source | MEDLINE; SAGE Complete A-Z List |
| subjects | Adult Aged Aspergillosis - microbiology Aspergillosis - physiopathology Aspergillosis - surgery Candidiasis - microbiology Candidiasis - physiopathology Candidiasis - surgery Endophthalmitis - microbiology Endophthalmitis - physiopathology Endophthalmitis - surgery Eye Infections, Fungal - microbiology Eye Infections, Fungal - physiopathology Eye Infections, Fungal - surgery Female Humans Male Middle Aged Reoperation Retinal Detachment - surgery Retrospective Studies Tertiary Care Centers Visual Acuity - physiology Vitrectomy - methods Vitreous Body - microbiology Young Adult |
| title | The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T02%3A59%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-sage_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20role%20of%20pars%20plana%20vitrectomy%20in%20the%20management%20of%20fungal%20endogenous%20endophthalmitis&rft.jtitle=European%20journal%20of%20ophthalmology&rft.au=Celiker,%20Hande&rft.date=2020-01-01&rft.volume=30&rft.issue=1&rft.spage=88&rft.epage=93&rft.pages=88-93&rft.issn=1120-6721&rft.eissn=1724-6016&rft_id=info:doi/10.1177/1120672118815105&rft_dat=%3Csage_cross%3E10.1177_1120672118815105%3C/sage_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/30474397&rft_sage_id=10.1177_1120672118815105&rfr_iscdi=true |