High-Throughput Analysis of HGF-Stimulated Cell Scattering

Historically, only relatively low-throughput or expensive methods have been available to measure cell migration. Hepatocyte growth factor (HGF) is a ligand for the tyrosine kinase receptor Met that, in addition to mediating proliferation and survival, increases cell motility and metastasis. The auth...

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Veröffentlicht in:	Journal of biomolecular screening 2008-10, Vol.13 (9), p.847-854
Hauptverfasser:	Chan, Grace K.Y., Lutterbach, Bart A., Pan, Bo-Sheng, Kariv, Ilona, Szewczak, Alexander A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Automation Cell Line, Tumor Cell Movement Cell Nucleus - metabolism Hepatocyte Growth Factor - metabolism Humans Image Cytometry - instrumentation Image Cytometry - methods Image Processing, Computer-Assisted Inhibitory Concentration 50 Ligands Models, Biological Pancreatic Neoplasms - metabolism Proto-Oncogene Proteins c-met - metabolism
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