Development and Implementation of a Highly Miniaturized Confocal 2D-FIDA–Based High-Throughput Screening Assay to Search for Active Site Modulators of the Human Heat Shock Protein 90β

The beta isoform of the heat shock protein 90 (Hsp90β) is a cellular chaperone required for the maturation of key proteins involved in growth response to extracellular factors as well as oncogenic transformation of various cell types. Compounds that inhibit the function of Hsp90β are thus believed t...

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Veröffentlicht in:	Journal of biomolecular screening 2004-10, Vol.9 (7), p.569-577
Hauptverfasser:	Schilb, Alain, Riou, Virginie, Schoepfer, Joseph, Ottl, Johannes, Müller, Kurt, Chene, Patrick, Mayr, Lorenz M., Filipuzzi, Ireos
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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