Improved Statistical Methods for Hit Selection in High-Throughput Screening

High-throughput screening (HTS) plays a central role in modern drug discovery, allowing the rapid screening of large compound collections against a variety of putative drug targets. HTS is an industrial-scale process, relying on sophisticated auto mation, control, and state-of-the art detection tech...

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Veröffentlicht in:	Journal of biomolecular screening 2003-12, Vol.8 (6), p.634-647
Hauptverfasser:	Brideau, Christine, Gunter, Bert, Pikounis, Bill, Liaw, Andy
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Drug Evaluation, Preclinical - methods Reference Standards Statistics as Topic - methods Temperature
Online-Zugang:	Volltext
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