Reproductive effects of fenoxycarb on sheep

Texas Veterinary Medical Diagnostic Lab, College Station 77841, USA. Fenoxycarb (ethyl [2-(4-phenoxyphenoxy)-ethyl] carbamate) is an insect growth regulator used for long-term fire ant control. Because of its effects on insect reproduction and its potential use on pasturage consumed by food animals,...

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Veröffentlicht in:Journal of veterinary diagnostic investigation 1997-10, Vol.9 (4), p.401-406
Hauptverfasser: Barr, A.C. (Texas Veterinary Medical Diagnostic Lab., College Station.), Abbitt, B, Fiske, R.A, Jaques, J.T, Maynard, H.R, Reagor, J.C
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container_end_page 406
container_issue 4
container_start_page 401
container_title Journal of veterinary diagnostic investigation
container_volume 9
creator Barr, A.C. (Texas Veterinary Medical Diagnostic Lab., College Station.)
Abbitt, B
Fiske, R.A
Jaques, J.T
Maynard, H.R
Reagor, J.C
description Texas Veterinary Medical Diagnostic Lab, College Station 77841, USA. Fenoxycarb (ethyl [2-(4-phenoxyphenoxy)-ethyl] carbamate) is an insect growth regulator used for long-term fire ant control. Because of its effects on insect reproduction and its potential use on pasturage consumed by food animals, a reproductive study was conducted using Rambouillet sheep. The sheep were dosed daily with a placebo or with fenoxycarb at 0.69 or 1.38 mg/kg/day, representing ten (10x) and 20 times (20x) the maximum amounts of fenoxycarb in forage or hay treated at recommended levels for fire ant control. Parameters that were measured included rates of weight gain of adults, serum clinical chemistry profiles of adults, spermatozoal morphology and motility, estrus cycling, pregnancy rates, maintenance of pregnancies to term, numbers of live births, and rates of weight gain of lambs to 28 days. There were no statistically significant (P
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(Texas Veterinary Medical Diagnostic Lab., College Station.) ; Abbitt, B ; Fiske, R.A ; Jaques, J.T ; Maynard, H.R ; Reagor, J.C</creator><creatorcontrib>Barr, A.C. (Texas Veterinary Medical Diagnostic Lab., College Station.) ; Abbitt, B ; Fiske, R.A ; Jaques, J.T ; Maynard, H.R ; Reagor, J.C</creatorcontrib><description>Texas Veterinary Medical Diagnostic Lab, College Station 77841, USA. Fenoxycarb (ethyl [2-(4-phenoxyphenoxy)-ethyl] carbamate) is an insect growth regulator used for long-term fire ant control. Because of its effects on insect reproduction and its potential use on pasturage consumed by food animals, a reproductive study was conducted using Rambouillet sheep. The sheep were dosed daily with a placebo or with fenoxycarb at 0.69 or 1.38 mg/kg/day, representing ten (10x) and 20 times (20x) the maximum amounts of fenoxycarb in forage or hay treated at recommended levels for fire ant control. Parameters that were measured included rates of weight gain of adults, serum clinical chemistry profiles of adults, spermatozoal morphology and motility, estrus cycling, pregnancy rates, maintenance of pregnancies to term, numbers of live births, and rates of weight gain of lambs to 28 days. There were no statistically significant (P</description><identifier>ISSN: 1040-6387</identifier><identifier>EISSN: 1943-4936</identifier><identifier>DOI: 10.1177/104063879700900410</identifier><identifier>PMID: 9376430</identifier><language>eng</language><publisher>Los Angeles, CA: J Vet Diagn Invest</publisher><subject>AGNEAU ; Animals ; BELIER ; Blood Chemical Analysis - veterinary ; BLOOD CHEMISTRY ; BLOOD COMPOSITION ; Body Weight - drug effects ; BREBIS ; CALOSTRO ; Carbamates - toxicity ; CICLO ESTRAL ; COLOSTRUM ; COMPOSICION DE LA SANGRE ; COMPOSITION DU SANG ; CORDERO ; CYCLE OESTRAL ; DOSAGE ; Dose-Response Relationship, Drug ; ESPERMATOZOO ; Estrus - drug effects ; EWES ; EXPOSURE ; Female ; FENOXICARB ; FENOXYCARB ; FENOXYCARBE ; Fetal Death - chemically induced ; Fetal Death - veterinary ; FOIE ; GAIN DE POIDS ; GANANCIA DE PESO ; GESTACION ; GESTATION ; HIGADO ; Insecticides - toxicity ; LAIT ; LAMBS ; LECHE ; LIVER ; LIVEWEIGHT GAIN ; Male ; MILK ; MORPHOLOGY ; MORUECO ; MOTILITY ; MOUVEMENT ; MOVEMENT ; MOVIMIENTO ; OESTROUS CYCLE ; Organ Size - drug effects ; OVEJA ; PERFORMANCE DE REPRODUCTION ; Phenylcarbamates ; PREGNANCY ; PREGNANCY RATE ; Pregnancy, Animal - drug effects ; RAMS ; Reproduction - drug effects ; REPRODUCTIVE PERFORMANCE ; REPRODUCTIVIDAD ; RESIDU ; RESIDUES ; RESIDUOS ; Sheep - physiology ; Sperm Motility - drug effects ; Spermatids - drug effects ; SPERMATOZOA ; Spermatozoa - cytology ; Spermatozoa - drug effects ; SPERMATOZOIDE ; TOXICIDAD ; TOXICITE ; TOXICITY ; WEIGHT GAIN ; Weight Gain - drug effects</subject><ispartof>Journal of veterinary diagnostic investigation, 1997-10, Vol.9 (4), p.401-406</ispartof><rights>1997 American Association of Veterinary Laboratory Diagnosticians</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-81db970eac894e8ff8b884c8ab4137f0472bfba3f049fd06e630131e85b350f93</citedby><cites>FETCH-LOGICAL-c434t-81db970eac894e8ff8b884c8ab4137f0472bfba3f049fd06e630131e85b350f93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9376430$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barr, A.C. (Texas Veterinary Medical Diagnostic Lab., College Station.)</creatorcontrib><creatorcontrib>Abbitt, B</creatorcontrib><creatorcontrib>Fiske, R.A</creatorcontrib><creatorcontrib>Jaques, J.T</creatorcontrib><creatorcontrib>Maynard, H.R</creatorcontrib><creatorcontrib>Reagor, J.C</creatorcontrib><title>Reproductive effects of fenoxycarb on sheep</title><title>Journal of veterinary diagnostic investigation</title><addtitle>J Vet Diagn Invest</addtitle><description>Texas Veterinary Medical Diagnostic Lab, College Station 77841, USA. Fenoxycarb (ethyl [2-(4-phenoxyphenoxy)-ethyl] carbamate) is an insect growth regulator used for long-term fire ant control. Because of its effects on insect reproduction and its potential use on pasturage consumed by food animals, a reproductive study was conducted using Rambouillet sheep. The sheep were dosed daily with a placebo or with fenoxycarb at 0.69 or 1.38 mg/kg/day, representing ten (10x) and 20 times (20x) the maximum amounts of fenoxycarb in forage or hay treated at recommended levels for fire ant control. Parameters that were measured included rates of weight gain of adults, serum clinical chemistry profiles of adults, spermatozoal morphology and motility, estrus cycling, pregnancy rates, maintenance of pregnancies to term, numbers of live births, and rates of weight gain of lambs to 28 days. There were no statistically significant (P</description><subject>AGNEAU</subject><subject>Animals</subject><subject>BELIER</subject><subject>Blood Chemical Analysis - veterinary</subject><subject>BLOOD CHEMISTRY</subject><subject>BLOOD COMPOSITION</subject><subject>Body Weight - drug effects</subject><subject>BREBIS</subject><subject>CALOSTRO</subject><subject>Carbamates - toxicity</subject><subject>CICLO ESTRAL</subject><subject>COLOSTRUM</subject><subject>COMPOSICION DE LA SANGRE</subject><subject>COMPOSITION DU SANG</subject><subject>CORDERO</subject><subject>CYCLE OESTRAL</subject><subject>DOSAGE</subject><subject>Dose-Response Relationship, Drug</subject><subject>ESPERMATOZOO</subject><subject>Estrus - drug effects</subject><subject>EWES</subject><subject>EXPOSURE</subject><subject>Female</subject><subject>FENOXICARB</subject><subject>FENOXYCARB</subject><subject>FENOXYCARBE</subject><subject>Fetal Death - chemically induced</subject><subject>Fetal Death - veterinary</subject><subject>FOIE</subject><subject>GAIN DE POIDS</subject><subject>GANANCIA DE PESO</subject><subject>GESTACION</subject><subject>GESTATION</subject><subject>HIGADO</subject><subject>Insecticides - toxicity</subject><subject>LAIT</subject><subject>LAMBS</subject><subject>LECHE</subject><subject>LIVER</subject><subject>LIVEWEIGHT GAIN</subject><subject>Male</subject><subject>MILK</subject><subject>MORPHOLOGY</subject><subject>MORUECO</subject><subject>MOTILITY</subject><subject>MOUVEMENT</subject><subject>MOVEMENT</subject><subject>MOVIMIENTO</subject><subject>OESTROUS CYCLE</subject><subject>Organ Size - drug effects</subject><subject>OVEJA</subject><subject>PERFORMANCE DE REPRODUCTION</subject><subject>Phenylcarbamates</subject><subject>PREGNANCY</subject><subject>PREGNANCY RATE</subject><subject>Pregnancy, Animal - drug effects</subject><subject>RAMS</subject><subject>Reproduction - drug effects</subject><subject>REPRODUCTIVE PERFORMANCE</subject><subject>REPRODUCTIVIDAD</subject><subject>RESIDU</subject><subject>RESIDUES</subject><subject>RESIDUOS</subject><subject>Sheep - physiology</subject><subject>Sperm Motility - drug effects</subject><subject>Spermatids - drug effects</subject><subject>SPERMATOZOA</subject><subject>Spermatozoa - cytology</subject><subject>Spermatozoa - drug effects</subject><subject>SPERMATOZOIDE</subject><subject>TOXICIDAD</subject><subject>TOXICITE</subject><subject>TOXICITY</subject><subject>WEIGHT GAIN</subject><subject>Weight Gain - drug effects</subject><issn>1040-6387</issn><issn>1943-4936</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9T11LwzAUDaLMOf0DgtAXn6Tupkmb5FHG_ICBoO45JO3N1rGtJdmm-_dmdOxF8OkeOB_3HEJuKTxSKsSQAoeCSaEEgALgFM5InyrOUq5YcR5xFKQHxSW5CmEBkGe5oD3SU0wUnEGfPHxg65tqW27qHSboHJabkDQucbhufval8TZp1kmYI7bX5MKZZcCb4x2Q6fP4a_SaTt5f3kZPk7TkjG9SSSsbG6EppeIonZNWSl5KYzllwgEXmXXWsIiUq6DAggFlFGVuWQ5OsQHJutzSNyF4dLr19cr4vaagD8P13-HRdNeZ2q1dYXWyHJdGftjxwcxQL5qtX8cN_yfed455PZt_1x51WJnlMuZnerGraqW55rH56bMzjTYzXwc9_aQqJuWQs4z9AlGRdRM</recordid><startdate>19971001</startdate><enddate>19971001</enddate><creator>Barr, A.C. (Texas Veterinary Medical Diagnostic Lab., College Station.)</creator><creator>Abbitt, B</creator><creator>Fiske, R.A</creator><creator>Jaques, J.T</creator><creator>Maynard, H.R</creator><creator>Reagor, J.C</creator><general>J Vet Diagn Invest</general><general>SAGE Publications</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19971001</creationdate><title>Reproductive effects of fenoxycarb on sheep</title><author>Barr, A.C. (Texas Veterinary Medical Diagnostic Lab., College Station.) ; Abbitt, B ; Fiske, R.A ; Jaques, J.T ; Maynard, H.R ; Reagor, J.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-81db970eac894e8ff8b884c8ab4137f0472bfba3f049fd06e630131e85b350f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>AGNEAU</topic><topic>Animals</topic><topic>BELIER</topic><topic>Blood Chemical Analysis - veterinary</topic><topic>BLOOD CHEMISTRY</topic><topic>BLOOD COMPOSITION</topic><topic>Body Weight - drug effects</topic><topic>BREBIS</topic><topic>CALOSTRO</topic><topic>Carbamates - toxicity</topic><topic>CICLO ESTRAL</topic><topic>COLOSTRUM</topic><topic>COMPOSICION DE LA SANGRE</topic><topic>COMPOSITION DU SANG</topic><topic>CORDERO</topic><topic>CYCLE OESTRAL</topic><topic>DOSAGE</topic><topic>Dose-Response Relationship, Drug</topic><topic>ESPERMATOZOO</topic><topic>Estrus - drug effects</topic><topic>EWES</topic><topic>EXPOSURE</topic><topic>Female</topic><topic>FENOXICARB</topic><topic>FENOXYCARB</topic><topic>FENOXYCARBE</topic><topic>Fetal Death - chemically induced</topic><topic>Fetal Death - veterinary</topic><topic>FOIE</topic><topic>GAIN DE POIDS</topic><topic>GANANCIA DE PESO</topic><topic>GESTACION</topic><topic>GESTATION</topic><topic>HIGADO</topic><topic>Insecticides - toxicity</topic><topic>LAIT</topic><topic>LAMBS</topic><topic>LECHE</topic><topic>LIVER</topic><topic>LIVEWEIGHT GAIN</topic><topic>Male</topic><topic>MILK</topic><topic>MORPHOLOGY</topic><topic>MORUECO</topic><topic>MOTILITY</topic><topic>MOUVEMENT</topic><topic>MOVEMENT</topic><topic>MOVIMIENTO</topic><topic>OESTROUS CYCLE</topic><topic>Organ Size - drug effects</topic><topic>OVEJA</topic><topic>PERFORMANCE DE REPRODUCTION</topic><topic>Phenylcarbamates</topic><topic>PREGNANCY</topic><topic>PREGNANCY RATE</topic><topic>Pregnancy, Animal - drug effects</topic><topic>RAMS</topic><topic>Reproduction - drug effects</topic><topic>REPRODUCTIVE PERFORMANCE</topic><topic>REPRODUCTIVIDAD</topic><topic>RESIDU</topic><topic>RESIDUES</topic><topic>RESIDUOS</topic><topic>Sheep - physiology</topic><topic>Sperm Motility - drug effects</topic><topic>Spermatids - drug effects</topic><topic>SPERMATOZOA</topic><topic>Spermatozoa - cytology</topic><topic>Spermatozoa - drug effects</topic><topic>SPERMATOZOIDE</topic><topic>TOXICIDAD</topic><topic>TOXICITE</topic><topic>TOXICITY</topic><topic>WEIGHT GAIN</topic><topic>Weight Gain - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barr, A.C. 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subjects AGNEAU
Animals
BELIER
Blood Chemical Analysis - veterinary
BLOOD CHEMISTRY
BLOOD COMPOSITION
Body Weight - drug effects
BREBIS
CALOSTRO
Carbamates - toxicity
CICLO ESTRAL
COLOSTRUM
COMPOSICION DE LA SANGRE
COMPOSITION DU SANG
CORDERO
CYCLE OESTRAL
DOSAGE
Dose-Response Relationship, Drug
ESPERMATOZOO
Estrus - drug effects
EWES
EXPOSURE
Female
FENOXICARB
FENOXYCARB
FENOXYCARBE
Fetal Death - chemically induced
Fetal Death - veterinary
FOIE
GAIN DE POIDS
GANANCIA DE PESO
GESTACION
GESTATION
HIGADO
Insecticides - toxicity
LAIT
LAMBS
LECHE
LIVER
LIVEWEIGHT GAIN
Male
MILK
MORPHOLOGY
MORUECO
MOTILITY
MOUVEMENT
MOVEMENT
MOVIMIENTO
OESTROUS CYCLE
Organ Size - drug effects
OVEJA
PERFORMANCE DE REPRODUCTION
Phenylcarbamates
PREGNANCY
PREGNANCY RATE
Pregnancy, Animal - drug effects
RAMS
Reproduction - drug effects
REPRODUCTIVE PERFORMANCE
REPRODUCTIVIDAD
RESIDU
RESIDUES
RESIDUOS
Sheep - physiology
Sperm Motility - drug effects
Spermatids - drug effects
SPERMATOZOA
Spermatozoa - cytology
Spermatozoa - drug effects
SPERMATOZOIDE
TOXICIDAD
TOXICITE
TOXICITY
WEIGHT GAIN
Weight Gain - drug effects
title Reproductive effects of fenoxycarb on sheep
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