N 4-Acyl-Modified D-2′,3′-Dideoxy-5-Fluorocytidine Nucleoside Analogues with Improved Antiviral Activity

A series of 2,3-dideoxy (D2) and 2,3-didehydro-2,3-dideoxy (D4) 5-fluorocytosine nucleosides modified with substituted benzoyl, heteroaromatic carbonyl, cycloalkylcarbonyl and alkanoyl at the N 4 -position were synthesized and evaluated for anti-human immunodeficiency virus type 1 (HIV-1) and anti-h...

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Veröffentlicht in:	Antiviral chemistry & chemotherapy 2003-04, Vol.14 (2), p.81-90
Hauptverfasser:	Shi, Junxing, Mathew, Judy S, Tharnish, Phillip M, Rachakonda, Suguna, Pai, S Balakrishna, Adams, Marjorie, Grier, Jason P, Gallagher, Karen, Zhang, Hangchun, Wu, Jing-Tao, Shi, Guoen, Geleziunas, Romas, Erickson-Viitanen, Susan, Stuyver, Lieven, Otto, Michael J, Watanabe, Kyoichi A, Schinazi, Raymond F
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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