Pulmonary Histopathology of Rats Following Parenteral Injections of Nickel Chloride

To elucidate the subacute toxic reactions to parenteral administration of Ni2+, male F-344 rats were given daily injections of NiCl2 (62.5 or 125 μmol/kg, sc) for 3 to 6 weeks. Nickel accumulation was greater in lung than in the other major organs, based upon tissue analyses by electrothermal atomic...

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Veröffentlicht in:	Toxicologic pathology 1988-01, Vol.16 (3), p.350-359
Hauptverfasser:	Knight, Joseph A., Rezuke, William N., Gillies, Concettina G., Hopfer, Sidney M., Sunderman, F. William
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Injections, Subcutaneous Lung - drug effects Lung - pathology Male Nickel - toxicity Rats Rats, Inbred F344
Online-Zugang:	Volltext
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