Recent Advancements and Applications of Human Immune System Mice in Preclinical Immuno-Oncology

Significant advances in immunotherapies have resulted in the increasing need of predictive preclinical models to improve immunotherapeutic drug development, treatment combination, and to prevent or minimize toxicity in clinical trials. Immunodeficient mice reconstituted with human immune system (HIS...

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Veröffentlicht in:	Toxicologic Pathology 2020-02, Vol.48 (2), p.302-316
Hauptverfasser:	Curran, Michelle, Mairesse, Maelle, Matas-Céspedes, Alba, Bareham, Bethany, Pellegrini, Giovanni, Liaunardy, Ardi, Powell, Edward, Sargeant, Rebecca, Cuomo, Emanuela, Stebbings, Richard, Betts, Catherine J., Saeb-Parsy, Kourosh
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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