The Effect of Azithromycin on the Pharmacokinetics of Indinavir

This study was performed to examine the effect of the coadministration of azithromycin on the pharmacokinetics of the protease inhibitor indinavir (Crixivan®). In an open‐label, parallel‐design study, 32 healthy male and female volunteers were given indinavir (800 mg tid) for 5 days. One hour prior...

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Veröffentlicht in:	Journal of clinical pharmacology 1999-08, Vol.39 (8), p.842-846
Hauptverfasser:	Foulds, George, LaBoy-Goral, Lucia, Wei, Greg C. G., Apseloff, Glen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Area Under Curve Azithromycin - adverse effects Azithromycin - pharmacology Biological and medical sciences Female Half-Life HIV Protease Inhibitors - pharmacokinetics Humans Indinavir - blood Indinavir - pharmacokinetics Male Medical sciences Patient Dropouts Pharmacology. Drug treatments Vomiting - chemically induced
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