Pentoxifylline Treatment in Patients with Occlusive Peripheral Arterial Disease. Circulatory Changes and Effects on Prostaglandin Synthesis

Pentoxifylline has recently been reported to stimulate in vitro the synthesis of prostacyclin. However it is not known so far whether the drug is able to stimulate prostacyclin synthesis in man also in vivo. In the present study the effects of pentoxifylline on prostaglandin synthesis and several ci...

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Veröffentlicht in:	Angiology 1985-09, Vol.36 (9), p.628-637
Hauptverfasser:	Poggesi, Loredana, Scarti, Luca, Boddi, Maria, Masotti, Giulio, Serneri, Gian Gastone Neri
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Ketoprostaglandin F1 alpha - blood Adult Arterial Occlusive Diseases - blood Arterial Occlusive Diseases - drug therapy Biological and medical sciences Blood Flow Velocity Cardiovascular system Clinical Trials as Topic Dinoprostone Drug Administration Schedule Erythrocyte Deformability Female Humans Leg - blood supply Male Medical sciences Middle Aged Pentoxifylline - administration & dosage Pentoxifylline - adverse effects Pentoxifylline - therapeutic use Pharmacology. Drug treatments Platelet Aggregation Prostaglandins - biosynthesis Prostaglandins E - blood Rest Theobromine - analogs & derivatives Vascular Resistance Vasodilator agents. Cerebral vasodilators
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