Protective effect of the thioltransferase gene on in vivo UVR-300 nm-induced cataract

To determine the protection factor (PF) for glutaredoxin-1 (Grx1) with regard to UVR-induced cataract by comparison of in vivo ultraviolet radiation (UVR) lens toxicity between double knockout Grx1⁻/⁻ and Grx1⁺/⁺ mice. Twenty Grx1⁺/⁺ mice and 20 Grx1⁻/⁻ mice were unilaterally exposed in vivo to UVR...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Investigative ophthalmology & visual science 2012-01, Vol.53 (1), p.248
Hauptverfasser:	Kronschläger, Martin, Galichanin, Konstantin, Ekström, Joakim, Lou, Marjorie F, Söderberg, Per G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cataract - etiology Cataract - prevention & control Gene Expression Regulation - physiology Glutaredoxins - genetics Lens, Crystalline - radiation effects Light Mice Mice, Inbred C57BL Mice, Knockout Oxidation-Reduction Radiation Injuries, Experimental - etiology Radiation Injuries, Experimental - prevention & control Scattering, Radiation Ultraviolet Rays - adverse effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!