Saffron Supplement Maintains Morphology and Function after Exposure to Damaging Light in Mammalian Retina

To test whether the saffron extract (Crocus sativus L.) given as a dietary supplement counteracts the effects of continuous light exposure in the albino rat retina. Three experimental groups of Sprague-Dawley rats were used. Experimental animals were prefed either saffron or beta-carotene (1 mg extr...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2008-03, Vol.49 (3), p.1254-1261
Hauptverfasser:	Maccarone, Rita, Di Marco, Stefano, Bisti, Silvia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects beta Carotene - administration & dosage Biological and medical sciences Blotting, Western Crocus Dark Adaptation Electroretinography Eye and associated structures. Visual pathways and centers. Vision Fibroblast Growth Factor 2 - metabolism Flowers Fluorescent Antibody Technique, Indirect Fundamental and applied biological sciences. Psychology In Situ Nick-End Labeling Light - adverse effects Medical sciences Ophthalmology Oxidative Stress Photic Stimulation Plant Extracts - administration & dosage Radiation Injuries, Experimental - metabolism Radiation Injuries, Experimental - pathology Radiation Injuries, Experimental - prevention & control Rats Rats, Sprague-Dawley Retina - physiology Retina - radiation effects Retinal Degeneration - metabolism Retinal Degeneration - pathology Retinal Degeneration - prevention & control Vertebrates: nervous system and sense organs
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