Safety Testing of Indocyanine Green and Trypan Blue Using Retinal Pigment Epithelium and Glial Cell Cultures

Indocyanine green (ICG) and trypan blue have been advocated as vital stains for use during macular surgery. The safety of these agents was tested using a cell culture model. Human retinal pigment epithelium (RPE) and Müller cell lines were exposed to ICG over a range of concentrations up to 0.5%, an...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2004-08, Vol.45 (8), p.2778-2785
Hauptverfasser:	Jackson, Timothy L, Hillenkamp, Jost, Knight, Bruce C, Zhang, Jin-Jun, Thomas, Dhanes, Stanford, Miles R, Marshall, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Line Cell Survival - drug effects Coloring Agents - toxicity Epistemology Fluoresceins - metabolism Fluorescent Dyes - metabolism Generalities Humans Indocyanine Green - toxicity Investigative techniques, diagnostic techniques (general aspects) Light Medical sciences Methodology and general studies Microscopy, Fluorescence Neuroglia - drug effects Neuroglia - radiation effects Organisation and history of research Otorhinolaryngology. Stomatology. Orbit Pigment Epithelium of Eye - drug effects Pigment Epithelium of Eye - radiation effects Prehistory and protohistory Radiodiagnosis. Nmr imagery. Nmr spectrometry Safety Trypan Blue - toxicity
Online-Zugang:	Volltext
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