The sensitivity of light-evoked responses of retinal ganglion cells is decreased in nitric oxide synthase gene knockout mice

We have shown previously that increasing the production of nitric oxide (NO) results in a dampening of visual responses of retinal ganglion cells (G. Y. Wang, L. C. Liets, & L. M. Chalupa, 2003). To gain further insights into the role of NO in retinal function, we made whole-cell patch clamp rec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of vision (Charlottesville, Va.) Va.), 2007-11, Vol.7 (14), p.7.1
Hauptverfasser:	Wang, Guo-Yong, van der List, Deborah A, Nemargut, Joseph P, Coombs, Julie L, Chalupa, Leo M
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Amacrine Cells - cytology Amacrine Cells - enzymology Animals Arginine - pharmacology Dark Adaptation - physiology Dose-Response Relationship, Radiation Enzyme Inhibitors - pharmacology Immunologic Techniques In Vitro Techniques Light Mice Mice, Inbred C57BL Mice, Knockout Models, Neurological NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide Synthase Type I - deficiency Nitric Oxide Synthase Type I - metabolism Patch-Clamp Techniques Retina - cytology Retina - metabolism Retinal Ganglion Cells - drug effects Retinal Ganglion Cells - physiology Retinal Ganglion Cells - radiation effects Signal Transduction - physiology Staining and Labeling
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!