Addition of 5% CO 2 to Inspiratory Gas Prevents Lung Injury in an Experimental Model of Pulmonary Artery Ligation

Unilateral ligation of the pulmonary artery may induce lung injury through multiple mechanisms, which might be dampened by inhaled CO . This study aims to characterize bilateral lung injury owing to unilateral ligation of the pulmonary artery in healthy swine undergoing controlled mechanical ventila...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2021-10, Vol.204 (8), p.933-942
Hauptverfasser:	Marongiu, Ines, Spinelli, Elena, Scotti, Eleonora, Mazzucco, Alessandra, Wang, Yu-Mei, Manesso, Leonardo, Colussi, Giulia, Biancolilli, Osvaldo, Battistin, Michele, Langer, Thomas, Roma, Francesca, Lopez, Gianluca, Lonati, Caterina, Vaira, Valentina, Rosso, Lorenzo, Ferrero, Stefano, Gatti, Stefano, Zanella, Alberto, Pesenti, Antonio, Mauri, Tommaso
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Animals Carbon Dioxide - therapeutic use Disease Models, Animal Female Ligation Lung Injury - etiology Lung Injury - physiopathology Lung Injury - prevention & control Lung Injury - therapy Protective Agents - therapeutic use Pulmonary Artery - surgery Respiration, Artificial - adverse effects Swine - surgery Treatment Outcome
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