Specific detection of tuberculosis infection: An interferon-γ-based assay using new antigens

The tuberculin skin test for immunologic diagnosis of Mycobacterium tuberculosis infection has many limitations, including being confounded by bacillus Calmette-Guérin (BCG) vaccination or exposure to nontuberculous mycobacteria. M. tuberculosis-specific antigens that are absent from BCG and most no...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2004-07, Vol.170 (1), p.59-64
Hauptverfasser:	MORI, Toru, SAKATANI, Mitsunori, SUZUKI, Katsuhiro, INOUE, Yoshikazu, TSUYUGUCHI, Kazunari, SASAKI, Yuka, MAZUREK, Gerald H, TSUYUGUCHI, Izuo, YAMAGISHI, Fumio, TAKASHIMA, Tetsuya, KAWABE, Yoshiko, NAGAO, Keiji, SHIGETO, Eriko, HARADA, Nobuyuki, MITARAI, Satoshi, OKADA, Masaji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens, Bacterial - immunology Bacterial Proteins - immunology BCG Vaccine - immunology Biological and medical sciences Cross Reactions Enzyme-Linked Immunosorbent Assay Epitopes Female Humans Immunoassay - methods Immunologic Memory Intensive care medicine Interferon-gamma - metabolism Male Medical sciences Mycobacterium tuberculosis - immunology Sensitivity and Specificity T-Lymphocytes - immunology Tuberculin Test Tuberculosis - diagnosis Vaccination
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