Prenatal Nicotine Exposure Blunts the Cardiorespiratory Response to Hypoxia in Lambs

Because smoking during pregnancy is a major risk factor for late fetal death and the sudden infant death syndrome, we investigated cardiorespiratory defense mechanisms to hypoxia in 7 prenatally nicotine-exposed (N) lambs (approximate maternal dose: 0.5 mg/kg/day) and 11 control (C) lambs all at an...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2002-12, Vol.166 (12), p.1544-1549
Hauptverfasser:	Hafstrom, Ola, Milerad, Joseph, Sundell, Hakan W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure - drug effects Chemoreceptor Cells - drug effects Female Heart Rate - drug effects Hypoxia - physiopathology Medical sciences Nicotine - administration & dosage Nicotine - blood Nicotine - toxicity Pregnancy Prenatal Exposure Delayed Effects Respiration - drug effects Sheep Tobacco, tobacco smoking Toxicology
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