Elimination of Severe Albuminuria in Aging Hypertensive Rats by Exchange of 2 Chromosomes in Double-Consomic Rats

The inherited nephron deficit and progressive albuminuria development observed in hypertensive Munich Wistar Frömter (MWF) rats are influenced by quantitative trait loci on rat chromosome (RNO) 6 and RNO8. Previous studies in young MWF rats suggested that the nephron deficit represents a cause for g...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2011-08, Vol.58 (2), p.219-224
Hauptverfasser:	van Es, Nicole, Schulz, Angela, IJpelaar, Daphne, van der Wal, Annemieke, Kuhn, Kristina, Schütten, Sabrina, Kossmehl, Peter, Nyengaard, Jens R, de Heer, Emile, Kreutz, Reinhold
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Aging - metabolism Albuminuria - genetics Albuminuria - metabolism Albuminuria - physiopathology Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - genetics Cardiology. Vascular system Desmin - genetics Desmin - metabolism Experimental diseases Hypertension - genetics Hypertension - metabolism Kidney Glomerulus - metabolism Kidney Glomerulus - physiopathology Male Medical sciences Quantitative Trait Loci Rats
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