Stromal cell-derived factor-1 retention and cardioprotection for ischemic myocardium

Stromal cell-derived factor-1 (SDF-1) is a chemoattractant of stem/progenitor cells, and several studies have shown that SDF-1 may improve ventricular function after infarction. SDF-1 is cleaved by proteases including matrix metalloproteinase-2 (MMP-2) and CD26/dipeptidylpeptidase-4 (DPP-4), which a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Circulation. Heart failure 2011-07, Vol.4 (4), p.509-518
Hauptverfasser:	Kanki, Sachiko, Segers, Vincent F M, Wu, Weitao, Kakkar, Rahul, Gannon, Joseph, Sys, Stanislas U, Sandrasagra, Anthony, Lee, Richard T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Capillaries - drug effects Chemokine CXCL12 - administration & dosage Chemokine CXCL12 - pharmacology Chemokine CXCL12 - therapeutic use Disease Models, Animal Dose-Response Relationship, Drug Heart - drug effects Heart - physiology Heart Failure - prevention & control Injections, Intra-Arterial Matrix Metalloproteinase 2 - metabolism Myocardial Reperfusion Injury - drug therapy Myocardial Reperfusion Injury - metabolism Myocardium - metabolism Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - physiology Rats Receptors, CXCR4 - metabolism Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!