Recombinant human soluble thrombomodulin and mortality in sepsis-induced disseminated intravascular coagulation. A multicentre retrospective study

Recombinant human soluble thrombomodulin (rhTM) is a novel class of anticoagulants for treating disseminated intravascular coagulation (DIC). Although rhTM is widely used in clinical settings throughout Japan, there is limited clinical evidence supporting the use of rhTM in patients with sepsis-indu...

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Veröffentlicht in:	Thrombosis and haemostasis 2016-06, Vol.115 (6), p.1157-1166
Hauptverfasser:	Hayakawa, Mineji, Yamakawa, Kazuma, Saito, Shinjiro, Uchino, Shigehiko, Kudo, Daisuke, Iizuka, Yusuke, Sanui, Masamitsu, Takimoto, Kohei, Mayumi, Toshihiko, Ono, Kota
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Disseminated Intravascular Coagulation - drug therapy Disseminated Intravascular Coagulation - etiology Disseminated Intravascular Coagulation - mortality Female Hospital Mortality Humans Japan - epidemiology Male Middle Aged Odds Ratio Propensity Score Recombinant Proteins - therapeutic use Retrospective Studies Sepsis - complications Solubility Thrombomodulin - therapeutic use Treatment Outcome
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