Functional role of a polymorphism in the Pannexin1 gene in collageninduced platelet aggregation

Summary Pannexin1 (Panx1) forms ATP channels that play a critical role in the immune response by reinforcing purinergic signal amplification in the immune synapse. Platelets express Panx1 and given the importance of ATP release in platelets, we investigated Panx1 function in platelet aggregation and...

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Veröffentlicht in:Thrombosis and haemostasis 2015, Vol.113 (2), p.325-336
Hauptverfasser: Molica, Filippo, Morel, Sandrine, Meens, Merlijn J., Denis, Jean-François, Bradfield, Paul F., Penuela, Silvia, Zufferey, Anne, Monyer, Hannah, Imhof, Beat A., Chanson, Marc, Laird, Dale W., Fontana, Pierre, Kwak, Brenda R.
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Sprache:eng
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