Male-specific cardiac pathologies in mice lacking either the A or B subunit of factor XIII

Summary Factor XIII (FXIII) is a proenzyme of plasma transglutaminase consisting of enzymatic A subunits (FXIII-A) and non-catalytic B subunits (FXIII-B), and acts in haemostasis and wound healing. We generated mice lacking either FXIII-A or FXIII-B to investigate the physiological functions of FXII...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Thrombosis and haemostasis 2008-02, Vol.99 (2), p.401-408
Hauptverfasser:	Souri, Masayoshi, Koseki-Kuno, Shiori, Takeda, Naoki, Yamakawa, Mitsunori, Takeishi, Yasuchika, Degen, Jay L., Ichinose, Akitada
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aging - blood Aging - pathology Animal Models Animals Biological and medical sciences Blood coagulation. Blood cells Echocardiography Factor XIII - genetics Factor XIII - metabolism Factor XIII Deficiency - blood Factor XIII Deficiency - complications Factor XIII Deficiency - genetics Factor XIII Deficiency - pathology Female Fibrosis Fundamental and applied biological sciences. Psychology gene-targeting GTP-Binding Proteins - metabolism Haemostasis Heart Diseases - blood Heart Diseases - etiology Heart Diseases - genetics Heart Diseases - pathology Hematologic and hematopoietic diseases Hematoma - blood Hematoma - etiology Hematoma - pathology Hemorrhage - blood Hemorrhage - etiology Hemorrhage - pathology Hemosiderin - metabolism Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Molecular and cellular biology Myocarditis - blood Myocarditis - etiology Myocarditis - pathology Myocardium - enzymology Myocardium - metabolism Myocardium - pathology Platelet diseases and coagulopathies Sex Factors Transglutaminase Transglutaminases - metabolism wound healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!