Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner

In mice, adenovirus (Ad)-elicited IFN-ab mediates the overproduction of LPS stimulated cytokines such as TNFa and IL-6. We found that Ad infection also mediates the overproduction of IFN-ab itself and enables its production in splenic marginal zone macrophages, which don't produce IFN-ab in res...

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Veröffentlicht in:	Journal of innate immunity 2024-03
Hauptverfasser:	Maler, Mareike D, Zwick, Sophie, Kallfass, Carsten, Engelhard, Peggy, Shi, Hexin, Hellig, Laura, Zhengyang, Pang, Hardt, Annika, Zissel, Gernot, Ruzsics, Zsolt, Jahnen-Dechent, Willi, Martin, Stefan F, Nielsen, Peter Jess, Stolz, Daiana, Lopatecka, Justyna, Bastyans, Sarah, Beutler, Bruce, Schamel, Wolfgang W, Fejer, György, Freudenberg, Marina Alexandra
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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