Mitochondrial Common Deletion Level in Adipose Tissue Is Not Associated with Obesity but Is Associated with a Structural Change in Triglycerides as Revealed by FTIR Spectroscopy

Abstract Objective: Several studies have shown that mitochondrial metabolism may be disrupted if the rate of the specific 4,977 bp deletion of mitochondrial DNA (mtDNA) reaches a threshold. This study aimed to investigate the possible associations between the mtDNA4977 deletion load and obesity-rela...

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Veröffentlicht in:	Medical Principles and Practice 2024-02, Vol.33 (1), p.74-82
Hauptverfasser:	Yılmaz, Ayda, Bahtiyar, Nurten, Doğan Mollaoğlu, Ayça, Zengin, Kagan, Taskin, Halit Eren, Karimova, Ayla, Baykara, Onur, Ulutin, Turgut, Onaran, Ilhan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissues Analysis Body fat Body mass index Fatty acids Fourier transforms Genetic testing Genomics Homeostasis Laparoscopy Lipids Metabolism Mitochondria Mitochondrial DNA Mutation Nucleotides Obesity Original Paper Oxidation Oxidative stress Physiological aspects Plasmids Polymerase chain reaction Proteins Spectrum analysis Surgery Triglycerides Type 2 diabetes Weight control
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