Periprocedural Peritonitis Prophylaxis: A Summary of the Microbiology and the Role of Systemic Antimicrobials

Background: Peritonitis is a leading complication of peritoneal dialysis (PD). One strategy that the International Society for Peritoneal Dialysis (ISPD) has used to help mitigate the morbidity and mortality associated with peritonitis is through prevention, including antibiotic prophylaxis utilizat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Kidney diseases 2021-03, Vol.7 (2), p.90-99
Hauptverfasser: Hsueh, Leon, Hu, Susie L., Shah, Ankur D.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 99
container_issue 2
container_start_page 90
container_title Kidney diseases
container_volume 7
creator Hsueh, Leon
Hu, Susie L.
Shah, Ankur D.
description Background: Peritonitis is a leading complication of peritoneal dialysis (PD). One strategy that the International Society for Peritoneal Dialysis (ISPD) has used to help mitigate the morbidity and mortality associated with peritonitis is through prevention, including antibiotic prophylaxis utilization in high-risk situations. The aim of this study is to summarize our current understanding of postprocedural peritonitis and discuss the existing data behind periprocedural antibiotic prophylaxis, focusing primarily on PD catheter insertion, dental procedures, colonoscopies, upper endoscopies with gastrostomy, and gynecologic procedures. Summary: The ISPD currently recommends intravenous antibiotics prior to PD catheter insertion, colonoscopies, and invasive gynecologic procedures, though prophylaxis has only demonstrated benefit in a prospective, randomized control setting for PD catheter insertion. However, multiple retrospective studies exist that support the use of antibiotic prophylaxis for the other 2 procedures. No specific antibiotic regimen has been established as most optimal to prevent peritonitis for any of the 3 procedures. Antibiotic coverage should include the Enterobacteriaceae family, as well as Gram-positive organisms commonly found on the skin flora for PD catheter insertion, anaerobes for colonoscopies, and common organisms from the urogenital flora in gynecologic procedures. Additionally, the ISPD currently recommends oral amoxicillin prior to dental procedures. There is currently no ISPD recommendation to provide antibiotic prophylaxis prior to an upper endoscopy with or without gastrostomy, though this is a potential area for research. Key Messages: PD patients are at high risk for developing peritonitis after typical procedures. Antibiotic prophylaxis is a potential strategy that the ISPD utilizes to prevent these infections. However, further research needs to be done to determine the optimal antibiotic regimen.
doi_str_mv 10.1159/000513773
format Article
fullrecord <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1159_000513773</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A726889341</galeid><doaj_id>oai_doaj_org_article_310c6099a3da4af89b28abc8e46ef6ea</doaj_id><sourcerecordid>A726889341</sourcerecordid><originalsourceid>FETCH-LOGICAL-c557t-1aaf1c757c543029e5427028da3b4197c23a3bfdf3f323d86c4962d78ff2e3b33</originalsourceid><addsrcrecordid>eNptkstv1DAQhyMEolXpgTtCkXqBwxY_4hcHpFVboKKIisLZcvzYdUniYCeI_e_rNCVipcqHGc9889N4PEXxEoJTCIl4BwAgEDOGnxSHCAm6Epiwp4vP4UFxnNJtxiCBgEH6vDjAmKOKU3ZYtNc2-j4Gbc0YVVNO1yF0fvCpvI6h3-4a9den9-W6vBnbVsVdGVw5bG351esYah-asNmVqjP3we-hsRNws0uDbb0u193g25lUTXpRPHPZ2OMHe1T8_Hjx4-zz6urbp8uz9dVKE8KGFVTKQc0I06TCAAlLKsQA4kbhuoKCaYSz54zDDiNsONWVoMgw7hyyuMb4qLicdU1Qt7KPfmpcBuXlfSDEjVRx8LqxEkOgKRBCYaMq5bioEVe15rai1lGrstaHWasf69YabbshD2pPdD_T-a3chD-SAwgQolngzYNADL9HmwbZ-qRt06jOhjFJRICggLBq6vtkRjcqt-Y7F7KinnC5ZohyLnAFM3X6CJWPmUYeOut8ju8VvJ0L8j-kFK1buodATksklyXK7Ov_n7uQ_1YmA69m4JeKGxsXYKk_eTT95fx8JmSf_-0OkZbWvQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2509605743</pqid></control><display><type>article</type><title>Periprocedural Peritonitis Prophylaxis: A Summary of the Microbiology and the Role of Systemic Antimicrobials</title><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Karger Open Access Journals</source><creator>Hsueh, Leon ; Hu, Susie L. ; Shah, Ankur D.</creator><creatorcontrib>Hsueh, Leon ; Hu, Susie L. ; Shah, Ankur D.</creatorcontrib><description>Background: Peritonitis is a leading complication of peritoneal dialysis (PD). One strategy that the International Society for Peritoneal Dialysis (ISPD) has used to help mitigate the morbidity and mortality associated with peritonitis is through prevention, including antibiotic prophylaxis utilization in high-risk situations. The aim of this study is to summarize our current understanding of postprocedural peritonitis and discuss the existing data behind periprocedural antibiotic prophylaxis, focusing primarily on PD catheter insertion, dental procedures, colonoscopies, upper endoscopies with gastrostomy, and gynecologic procedures. Summary: The ISPD currently recommends intravenous antibiotics prior to PD catheter insertion, colonoscopies, and invasive gynecologic procedures, though prophylaxis has only demonstrated benefit in a prospective, randomized control setting for PD catheter insertion. However, multiple retrospective studies exist that support the use of antibiotic prophylaxis for the other 2 procedures. No specific antibiotic regimen has been established as most optimal to prevent peritonitis for any of the 3 procedures. Antibiotic coverage should include the Enterobacteriaceae family, as well as Gram-positive organisms commonly found on the skin flora for PD catheter insertion, anaerobes for colonoscopies, and common organisms from the urogenital flora in gynecologic procedures. Additionally, the ISPD currently recommends oral amoxicillin prior to dental procedures. There is currently no ISPD recommendation to provide antibiotic prophylaxis prior to an upper endoscopy with or without gastrostomy, though this is a potential area for research. Key Messages: PD patients are at high risk for developing peritonitis after typical procedures. Antibiotic prophylaxis is a potential strategy that the ISPD utilizes to prevent these infections. However, further research needs to be done to determine the optimal antibiotic regimen.</description><identifier>ISSN: 2296-9381</identifier><identifier>EISSN: 2296-9357</identifier><identifier>DOI: 10.1159/000513773</identifier><identifier>PMID: 33824867</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Amoxicillin ; Anti-infective agents ; antibiotics ; Catheterization ; Colonoscopy ; Health aspects ; Medical research ; Medicine, Experimental ; Microbiology ; Microbiota (Symbiotic organisms) ; Mortality ; periprocedure ; peritoneal dialysis ; Peritonitis ; Prevention ; Review ; Review Article</subject><ispartof>Kidney diseases, 2021-03, Vol.7 (2), p.90-99</ispartof><rights>2021 The Author(s) Published by S. Karger AG, Basel</rights><rights>Copyright © 2021 by S. Karger AG, Basel.</rights><rights>COPYRIGHT 2021 S. Karger AG</rights><rights>Copyright © 2021 by S. Karger AG, Basel 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c557t-1aaf1c757c543029e5427028da3b4197c23a3bfdf3f323d86c4962d78ff2e3b33</citedby><cites>FETCH-LOGICAL-c557t-1aaf1c757c543029e5427028da3b4197c23a3bfdf3f323d86c4962d78ff2e3b33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010226/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010226/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,27635,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33824867$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hsueh, Leon</creatorcontrib><creatorcontrib>Hu, Susie L.</creatorcontrib><creatorcontrib>Shah, Ankur D.</creatorcontrib><title>Periprocedural Peritonitis Prophylaxis: A Summary of the Microbiology and the Role of Systemic Antimicrobials</title><title>Kidney diseases</title><addtitle>Kidney Dis</addtitle><description>Background: Peritonitis is a leading complication of peritoneal dialysis (PD). One strategy that the International Society for Peritoneal Dialysis (ISPD) has used to help mitigate the morbidity and mortality associated with peritonitis is through prevention, including antibiotic prophylaxis utilization in high-risk situations. The aim of this study is to summarize our current understanding of postprocedural peritonitis and discuss the existing data behind periprocedural antibiotic prophylaxis, focusing primarily on PD catheter insertion, dental procedures, colonoscopies, upper endoscopies with gastrostomy, and gynecologic procedures. Summary: The ISPD currently recommends intravenous antibiotics prior to PD catheter insertion, colonoscopies, and invasive gynecologic procedures, though prophylaxis has only demonstrated benefit in a prospective, randomized control setting for PD catheter insertion. However, multiple retrospective studies exist that support the use of antibiotic prophylaxis for the other 2 procedures. No specific antibiotic regimen has been established as most optimal to prevent peritonitis for any of the 3 procedures. Antibiotic coverage should include the Enterobacteriaceae family, as well as Gram-positive organisms commonly found on the skin flora for PD catheter insertion, anaerobes for colonoscopies, and common organisms from the urogenital flora in gynecologic procedures. Additionally, the ISPD currently recommends oral amoxicillin prior to dental procedures. There is currently no ISPD recommendation to provide antibiotic prophylaxis prior to an upper endoscopy with or without gastrostomy, though this is a potential area for research. Key Messages: PD patients are at high risk for developing peritonitis after typical procedures. Antibiotic prophylaxis is a potential strategy that the ISPD utilizes to prevent these infections. However, further research needs to be done to determine the optimal antibiotic regimen.</description><subject>Amoxicillin</subject><subject>Anti-infective agents</subject><subject>antibiotics</subject><subject>Catheterization</subject><subject>Colonoscopy</subject><subject>Health aspects</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Microbiology</subject><subject>Microbiota (Symbiotic organisms)</subject><subject>Mortality</subject><subject>periprocedure</subject><subject>peritoneal dialysis</subject><subject>Peritonitis</subject><subject>Prevention</subject><subject>Review</subject><subject>Review Article</subject><issn>2296-9381</issn><issn>2296-9357</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>M--</sourceid><sourceid>DOA</sourceid><recordid>eNptkstv1DAQhyMEolXpgTtCkXqBwxY_4hcHpFVboKKIisLZcvzYdUniYCeI_e_rNCVipcqHGc9889N4PEXxEoJTCIl4BwAgEDOGnxSHCAm6Epiwp4vP4UFxnNJtxiCBgEH6vDjAmKOKU3ZYtNc2-j4Gbc0YVVNO1yF0fvCpvI6h3-4a9den9-W6vBnbVsVdGVw5bG351esYah-asNmVqjP3we-hsRNws0uDbb0u193g25lUTXpRPHPZ2OMHe1T8_Hjx4-zz6urbp8uz9dVKE8KGFVTKQc0I06TCAAlLKsQA4kbhuoKCaYSz54zDDiNsONWVoMgw7hyyuMb4qLicdU1Qt7KPfmpcBuXlfSDEjVRx8LqxEkOgKRBCYaMq5bioEVe15rai1lGrstaHWasf69YabbshD2pPdD_T-a3chD-SAwgQolngzYNADL9HmwbZ-qRt06jOhjFJRICggLBq6vtkRjcqt-Y7F7KinnC5ZohyLnAFM3X6CJWPmUYeOut8ju8VvJ0L8j-kFK1buodATksklyXK7Ov_n7uQ_1YmA69m4JeKGxsXYKk_eTT95fx8JmSf_-0OkZbWvQ</recordid><startdate>20210301</startdate><enddate>20210301</enddate><creator>Hsueh, Leon</creator><creator>Hu, Susie L.</creator><creator>Shah, Ankur D.</creator><general>S. Karger AG</general><general>Karger Publishers</general><scope>M--</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20210301</creationdate><title>Periprocedural Peritonitis Prophylaxis: A Summary of the Microbiology and the Role of Systemic Antimicrobials</title><author>Hsueh, Leon ; Hu, Susie L. ; Shah, Ankur D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c557t-1aaf1c757c543029e5427028da3b4197c23a3bfdf3f323d86c4962d78ff2e3b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Amoxicillin</topic><topic>Anti-infective agents</topic><topic>antibiotics</topic><topic>Catheterization</topic><topic>Colonoscopy</topic><topic>Health aspects</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Microbiology</topic><topic>Microbiota (Symbiotic organisms)</topic><topic>Mortality</topic><topic>periprocedure</topic><topic>peritoneal dialysis</topic><topic>Peritonitis</topic><topic>Prevention</topic><topic>Review</topic><topic>Review Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hsueh, Leon</creatorcontrib><creatorcontrib>Hu, Susie L.</creatorcontrib><creatorcontrib>Shah, Ankur D.</creatorcontrib><collection>Karger Open Access Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Kidney diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hsueh, Leon</au><au>Hu, Susie L.</au><au>Shah, Ankur D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Periprocedural Peritonitis Prophylaxis: A Summary of the Microbiology and the Role of Systemic Antimicrobials</atitle><jtitle>Kidney diseases</jtitle><addtitle>Kidney Dis</addtitle><date>2021-03-01</date><risdate>2021</risdate><volume>7</volume><issue>2</issue><spage>90</spage><epage>99</epage><pages>90-99</pages><issn>2296-9381</issn><eissn>2296-9357</eissn><abstract>Background: Peritonitis is a leading complication of peritoneal dialysis (PD). One strategy that the International Society for Peritoneal Dialysis (ISPD) has used to help mitigate the morbidity and mortality associated with peritonitis is through prevention, including antibiotic prophylaxis utilization in high-risk situations. The aim of this study is to summarize our current understanding of postprocedural peritonitis and discuss the existing data behind periprocedural antibiotic prophylaxis, focusing primarily on PD catheter insertion, dental procedures, colonoscopies, upper endoscopies with gastrostomy, and gynecologic procedures. Summary: The ISPD currently recommends intravenous antibiotics prior to PD catheter insertion, colonoscopies, and invasive gynecologic procedures, though prophylaxis has only demonstrated benefit in a prospective, randomized control setting for PD catheter insertion. However, multiple retrospective studies exist that support the use of antibiotic prophylaxis for the other 2 procedures. No specific antibiotic regimen has been established as most optimal to prevent peritonitis for any of the 3 procedures. Antibiotic coverage should include the Enterobacteriaceae family, as well as Gram-positive organisms commonly found on the skin flora for PD catheter insertion, anaerobes for colonoscopies, and common organisms from the urogenital flora in gynecologic procedures. Additionally, the ISPD currently recommends oral amoxicillin prior to dental procedures. There is currently no ISPD recommendation to provide antibiotic prophylaxis prior to an upper endoscopy with or without gastrostomy, though this is a potential area for research. Key Messages: PD patients are at high risk for developing peritonitis after typical procedures. Antibiotic prophylaxis is a potential strategy that the ISPD utilizes to prevent these infections. However, further research needs to be done to determine the optimal antibiotic regimen.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>33824867</pmid><doi>10.1159/000513773</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2296-9381
ispartof Kidney diseases, 2021-03, Vol.7 (2), p.90-99
issn 2296-9381
2296-9357
language eng
recordid cdi_crossref_primary_10_1159_000513773
source DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Karger Open Access Journals
subjects Amoxicillin
Anti-infective agents
antibiotics
Catheterization
Colonoscopy
Health aspects
Medical research
Medicine, Experimental
Microbiology
Microbiota (Symbiotic organisms)
Mortality
periprocedure
peritoneal dialysis
Peritonitis
Prevention
Review
Review Article
title Periprocedural Peritonitis Prophylaxis: A Summary of the Microbiology and the Role of Systemic Antimicrobials
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T17%3A30%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Periprocedural%20Peritonitis%20Prophylaxis:%20A%20Summary%20of%20the%20Microbiology%20and%20the%20Role%20of%20Systemic%20Antimicrobials&rft.jtitle=Kidney%20diseases&rft.au=Hsueh,%20Leon&rft.date=2021-03-01&rft.volume=7&rft.issue=2&rft.spage=90&rft.epage=99&rft.pages=90-99&rft.issn=2296-9381&rft.eissn=2296-9357&rft_id=info:doi/10.1159/000513773&rft_dat=%3Cgale_cross%3EA726889341%3C/gale_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2509605743&rft_id=info:pmid/33824867&rft_galeid=A726889341&rft_doaj_id=oai_doaj_org_article_310c6099a3da4af89b28abc8e46ef6ea&rfr_iscdi=true