Efficacy, Safety, and Tolerability of Armodafinil Therapy for Hypersomnia Associated with Dementia with Lewy Bodies: A Pilot Study

Background/Aims: Hypersomnia is common in dementia with Lewy bodies (DLB). We assessed the efficacy, safety, and tolerability of armodafinil for hypersomnia associated with DLB. Methods: We performed a 12-week pilot trial of armodafinil therapy (125-250 mg orally daily) in DLB outpatients with hyper...

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Veröffentlicht in:	Dementia and geriatric cognitive disorders 2017-01, Vol.43 (5-6), p.269-280
Hauptverfasser:	Lapid, Maria I., Kuntz, Karen M., Mason, Sara S., Aakre, Jeremiah A., Lundt, Emily S., Kremers, Walter, Allen, Laura A., Drubach, Daniel A., Boeve, Bradley F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living Aged Analysis Armodafinil Batteries Benzhydryl Compounds - administration & dosage Benzhydryl Compounds - adverse effects Care and treatment Caregivers Clinical trials Complications and side effects Dementia Disorders of Excessive Somnolence - diagnosis Disorders of Excessive Somnolence - drug therapy Disorders of Excessive Somnolence - etiology Drug Monitoring - methods Electrocardiography Female Hallucinations Heart rate Humans Hypersomnia Lewy Body Disease - diagnosis Lewy Body Disease - drug therapy Lewy Body Disease - physiopathology Lewy Body Disease - psychology Male Married people Medical research Memantine Neurologic Examination - methods Original Research Article Outpatients - psychology Outpatients - statistics & numerical data Pilot Projects Polysomnography - methods Quality of Life Treatment Outcome Wakefulness - drug effects Wakefulness-Promoting Agents - administration & dosage Wakefulness-Promoting Agents - adverse effects
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