Antibacterial Defense of Human Airway Epithelial Cells from Chronic Obstructive Pulmonary Disease Patients Induced by Acute Exposure to Nontypeable Haemophilus influenzae: Modulation by Cigarette Smoke

Antimicrobial proteins and peptides (AMPs) are a central component of the antibacterial activity of airway epithelial cells. It has been proposed that a decrease in antibacterial lung defense contributes to an increased susceptibility to microbial infection in smokers and patients with chronic obstr...

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Veröffentlicht in:Journal of innate immunity 2017-01, Vol.9 (4), p.359-374
Hauptverfasser: Amatngalim, Gimano D., Schrumpf, Jasmijn A., Henic, Almira, Dronkers, Esther, Verhoosel, Renate M., Ordonez, Soledad R., Haagsman, Henk P., Fuentes, Maria E., Sridhar, Sriram, Aarbiou, Jamil, Janssen, Richard A.J., Lekkerkerker, Annemarie N., Hiemstra, Pieter S.
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Sprache:eng
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