Myeloid Sarcoma of the Hepatobiliary System: A Case Series and Review of the Literature

Myeloid Sarcoma of the Hepatobiliary System: A Case Series and Review of the Literature

Myeloid sarcoma (MS) is a rare extramedullary presentation of myeloid malignancies, most commonly seen in association with acute myeloid leukemia (AML). Although MS can develop in any organ, the involvement of the hepatobiliary system is rare. With clinical manifestations of jaundice, abdominal pain...

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Veröffentlicht in:Acta haematologica 2016-01, Vol.135 (4), p.241-251
Hauptverfasser: Norsworthy, Kelly J., Bhatnagar, Bhavana, Singh, Zeba N., Gojo, Ivana
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Sprache:eng
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Humans
Jaundice
Leukemia, Myeloid, Acute
Review
Sarcoma, Myeloid - diagnosis
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container_issue 4
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container_title Acta haematologica
container_volume 135
creator Norsworthy, Kelly J.
Bhatnagar, Bhavana
Singh, Zeba N.
Gojo, Ivana
description Myeloid sarcoma (MS) is a rare extramedullary presentation of myeloid malignancies, most commonly seen in association with acute myeloid leukemia (AML). Although MS can develop in any organ, the involvement of the hepatobiliary system is rare. With clinical manifestations of jaundice, abdominal pain and other gastrointestinal symptoms, MS presenting at this location can be a challenge to diagnose, particularly in patients with no known history of hematologic malignancy. This may cause delay in proper management. Here we report 3 cases from a single institution and a review of the literature concerning the epidemiology, clinical presentation, treatment and outcomes in patients with MS of the liver, biliary tree and pancreas.
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subjects Humans
Jaundice
Leukemia, Myeloid, Acute
Review
Sarcoma, Myeloid - diagnosis
title Myeloid Sarcoma of the Hepatobiliary System: A Case Series and Review of the Literature
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