Tissue Transglutaminase, Not Lysyl Oxidase, Dominates Early Calcium-Dependent Remodeling of Fibroblast-Populated Collagen Lattices

Cell-populated collagen gels have provided significant insight into the cellular contractile mechanisms and cell-matrix interactions that are necessary for compacting and remodeling extant matrix. Nevertheless, little research has been devoted towards determining how cells entrench these deformation...

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Veröffentlicht in:	Cells, tissues, organs tissues, organs, 2014-01, Vol.200 (2), p.104-117
Hauptverfasser:	Simon, D.D., Niklason, L.E., Humphrey, J.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Cell Survival - drug effects Collagen - pharmacology Cross-Linking Reagents - pharmacology Extracellular Matrix - drug effects Extracellular Matrix - metabolism Fibroblasts - drug effects Fibroblasts - enzymology GTP-Binding Proteins - metabolism Mice NIH 3T3 Cells Original Paper Protein-Lysine 6-Oxidase - metabolism Rats Time Factors Transglutaminases - metabolism
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