Restoration of Epigenetically Silenced Sulfatase 1 Expression by 5-Aza-2′-Deoxycytidine Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy-Induced Apoptosis

Background: Hepatocellular carcinoma (HCC) is the second most frequent cause of cancer death worldwide. Sulfatase 1 (SULF1) functions as a tumor suppressor in HCC cell lines in vitro but also has an oncogenic effect in some HCCs in vivo. Aim: The purpose of this study was to examine the mechanisms r...

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Veröffentlicht in:	Medical epigenetics 2015-04, Vol.3 (1), p.1-18
Hauptverfasser:	Shire, Abdirashid, Lomberk, Gwen, Lai, Jin-Ping, Zou, Hongzhi, Tsuchiya, Norihiko, Aderca, Ileana, Moser, Catherine D., Gulaid, Kadra H., Oseini, Abdul, Hu, Chunling, Warsame, Omar, Jenkins, Robert B., Roberts, Lewis R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Paper
Online-Zugang:	Volltext
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