Prodifferentiation, Anti-Inflammatory and Antiproliferative Effects of Delphinidin, a Dietary Anthocyanidin, in a Full-Thickness Three-Dimensional Reconstituted Human Skin Model of Psoriasis

Background: Psoriasis is a chronic inflammatory disorder of skin and joints for which conventional treatments that are effective in clearing the moderate-to-severe disease are limited due to long-term safety issues. This necessitates exploring the usefulness of botanical agents for treating psoriasi...

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Veröffentlicht in:	Skin pharmacology and physiology 2015-01, Vol.28 (4), p.177-188
Hauptverfasser:	Chamcheu, Jean Christopher, Pal, Harish C., Siddiqui, Imtiaz A., Adhami, Vaqar M., Ayehunie, Seyoum, Boylan, Brendan T., Noubissi, Felicite K., Khan, Naghma, Syed, Deeba N., Elmets, Craig A., Wood, Gary S., Afaq, Farrukh, Mukhtar, Hasan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthocyanins - pharmacology Anti-Inflammatory Agents - pharmacology Caspases - genetics Caspases - metabolism Cell Differentiation Cells, Cultured Cytokines - metabolism Humans Keratinocytes - drug effects Keratinocytes - metabolism Membrane Proteins - genetics Membrane Proteins - metabolism Models, Biological Original Paper Protein Precursors - genetics Protein Precursors - metabolism Psoriasis - drug therapy Psoriasis - metabolism RNA, Messenger - metabolism S100 Proteins - genetics Skin - drug effects Skin - metabolism
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